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Prolactin receptor regulates the seasonal reproduction of striped hamsters

Published online by Cambridge University Press:  22 June 2021

Huiliang Xue ,
Jinhui Xu ,
Ming Wu ,
Lei Chen  and
Laixiang Xu Open the ORCID record for Laixiang Xu [Opens in a new window]
Huiliang Xue
Affiliation:
College of Life Sciences, Qufu Normal University, Qufu, Shandong Province 273165, China
Jinhui Xu
Affiliation:
College of Life Sciences, Qufu Normal University, Qufu, Shandong Province 273165, China
Ming Wu
Affiliation:
College of Life Sciences, Qufu Normal University, Qufu, Shandong Province 273165, China
Lei Chen
Affiliation:
College of Life Sciences, Qufu Normal University, Qufu, Shandong Province 273165, China
Laixiang Xu*
Affiliation:
College of Life Sciences, Qufu Normal University, Qufu, Shandong Province 273165, China
*
Author for correspondence: Laixiang Xu. College of Life Sciences, Qufu Normal University, No. 57 Jingxuan West Road, Qufu, Shandong Province 273165, China. Tel: +86 0537 4458169. Email: xulx@qfnu.edu.cn
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Summary

In this study, differential mRNA expression patterns of prolactin receptor (PRLR) in the hypothalamus and gonads, and the correlation with follicle stimulating hormone (FSH) and luteinizing hormone (LH) in striped hamster serum from spring, summer, autumn and winter were analyzed. Mature female and male striped hamsters in oestrus were used. Expression levels of PRLR in the hypothalamus, ovaries and testis from the summer and winter individuals were significantly higher compared with levels from the spring and autumn, whereas FSH and LH serum concentrations from summer and winter individuals were significantly lower compared with that from the spring and autumn. PRLR expression levels in hypothalamus, ovaries and testis were negatively correlated with FSH and LH serum concentrations, illustrating that PRLR might negatively regulate seasonal reproductive activity. PRLR expression levels in ovaries and testes were significantly higher compared with levels in the hypothalamus, suggesting that the regulative effects of PRLR in gonads might be significantly higher compared with that in the hypothalamus. Furthermore, PRLR expression levels from the spring, summer, autumn and winter seasons in the hypothalamus and gonads were significantly higher in females compared with levels in males, indicating that the regulative effect of PRLR might be sex dependent. Taken together, this study helps to understand in depth the seasonal regulative reproduction mechanism of striped hamsters to reasonably control population abundance.

Keywords

PRLRSeasonal reproductionSexStriped Hamsters
Type
Research Article
Information
Zygote , Volume 30 , Issue 1 , February 2022 , pp. 40 - 47
Copyright
© The Author(s), 2021. Published by Cambridge University Press

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