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Study of HLA Antigens Among Japanese Schizophrenics

Published online by Cambridge University Press:  29 January 2018

Akio Asaka
Affiliation:
Institute of Brain Research, University of Tokyo School of Medicine, Bunkyo-ku, Tokyo, Japan
Yuji Okazaki
Affiliation:
Department of Neuropsychiatry, Tokyo University Hospital, Bunkyo-ku, Tokyo, Japan
Ikuro Namura
Affiliation:
Department of Neuropsychiatry, Tokyo University Hospital
Takeo Juji
Affiliation:
Blood Transfusion Service, Toyko University Hospital
Mitsuko Miyamoto
Affiliation:
Blood Transfusion Service, Tokyo University Hospital
Bun-Noshin Ishikawa
Affiliation:
Utsunomiya Mental Hospital, Utsunomiya City, Tochigi Prefecture, Japan

Summary

HLA antigens were typed among 136 Japanese schizophrenics. Increased frequencies were seen in A9 (Aw24), A10 (A26) and Bw54, and decreased frequency in B40 antigens when compared to 187 Japanese controls. It is suggested that there may be an association between A9 (Aw24) and schizophrenia with a chronic-progressive course and also an association between A10 (A26) and hebephrenia.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1981 

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