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Metabotropic glutamate receptor agonists for schizophrenia

Published online by Cambridge University Press:  02 January 2018

Paul J. Harrison*
Affiliation:
Department of Psychiatry, Warneford Hospital, Oxford OX3 7JX, UK. Email: paul.harrison@psych.ox.ac.uk
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Summary

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A drug acting at metabotropic glutamate receptors has recently been reported to be an effective antipsychotic, breaking the rule that only dopamine receptor-blocking drugs have this property. The finding complements accumulating evidence that glutamatergic abnormalities are important in the pathophysiology of schizophrenia.

Type
Editorials
Copyright
Copyright © Royal College of Psychiatrists, 2008 

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