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Global, regional and national burdens of depression in adolescents and young adults aged 10–24 years, from 1990 to 2019: findings from the 2019 Global Burden of Disease study
Published online by Cambridge University Press: 25 April 2024
Abstract
Background
Depression is a significant mental health concern affecting the overall well-being of adolescents and young adults. Recently, the prevalence of depression has increased among young people. Nonetheless, there is little research delving into the longitudinal epidemiology of adolescent depression over time.
Aims
To investigate the longitudinal epidemiology of depression among adolescents and young adults aged 10–24 years.
Method
Our research focused on young people (aged 10–24 years) with depression, using data from the Global Burden of Diseases, Injuries, and Risk Factors Study 2019. We explored the age-standardised prevalence, incidence and disability-adjusted life-years (DALYs) of depression in different groups, including various regions, ages, genders and sociodemographic indices, from 1990 to 2019.
Results
The prevalence, incidence and DALYs of depression in young people increased globally between 1990 and 2019. Regionally, higher-income regions like High-Income North America and Australasia recorded rising age-standardised prevalence and incidence rates, whereas low- or middle-income regions mostly saw reductions. Nationally, countries such as Greenland, the USA and Palestine reported the highest age-standardised prevalence and incidence rates in 2019, whereas Qatar witnessed the largest growth over time. The burden disproportionately affected females across age groups and world regions. The most prominent age effect on incidence and prevalence rates was in those aged 20–24 years. The depression burden showed an unfavourable trend in younger cohorts born after 1980, with females reporting a higher cohort risk than males.
Conclusions
Between 1990 and 2019, the general pattern of depression among adolescents varied according to age, gender, time period and generational cohort, across regions and nations.
Keywords
- Type
- Original Article
- Information
- Copyright
- Copyright © The Author(s), 2024. Published by Cambridge University Press on behalf of Royal College of Psychiatrists
Footnotes
*
Joint first authors.
†
Joint senior authors.
References
Mojtabai, R, Olfson, M, Han, B. National trends in the prevalence and treatment of depression in adolescents and young adults. Pediatrics 2016; 138(6): e20161878.CrossRefGoogle ScholarPubMed
Chi, X, Bo, A, Liu, T, Zhang, P, Chi, I Effects of mindfulness-based stress reduction on depression in adolescents and young adults: a systematic review and meta-analysis. Front Psychol 2018; 9: 1034.CrossRefGoogle Scholar
GBD 2019 Mental Disorders Collaborators. Global, regional, and national burden of 12 mental disorders in 204 countries and territories, 1990–2019: a systematic analysis for the global burden of disease study 2019. Lancet Psychiatry 2022; 9(2): 137–50.CrossRefGoogle Scholar
GBD 2017 Disease and Injury Incidence and Prevalence Collaborators. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the global burden of disease study 2017. Lancet 2018; 392(10159): 1789–858.CrossRefGoogle Scholar
Mackner, LM, Whitaker, BN, Maddux, MH, Thompson, S, Hughes-Reid, C, Drovetta, M, et al. Depression screening in pediatric inflammatory bowel disease clinics: recommendations and a toolkit for implementation. J Pediatr Gastr Nutr 2020; 70(1): 42–7.CrossRefGoogle Scholar
COVID-19 Mental Disorders Collaborators. Global prevalence and burden of depressive and anxiety disorders in 204 countries and territories in 2020 due to the COVID-19 pandemic. Lancet 2021; 398(10312): 1700–12.CrossRefGoogle Scholar
GBD, 2019 Diseases and Injuries Collaborators. Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease study 2019. Lancet 2020; 396(10258): 1204–22.Google Scholar
Ren, X, Yu, S, Dong, W, Yin, P, Xu, X, Zhou, M Burden of depression in China, 1990–2017: findings from the global burden of disease study 2017. J Affect Disorders 2020; 268: 95–101.CrossRefGoogle Scholar
Zhang, K, Kan, C, Han, F, Zhang, J, Ding, C, Guo, Z, et al. Global, regional, and national epidemiology of diabetes in children from 1990 to 2019. JAMA Pediatr 2023; 177(8): 837–46.CrossRefGoogle ScholarPubMed
Lai, J, Li, S, Wei, C, Chen, J, Fang, Y, Song, P, et al. Mapping the global, regional and national burden of bipolar disorder from 1990 to 2019: trend analysis on the global burden of disease study 2019. Br J Psychiatry 2024; 224(2): 36–46.CrossRefGoogle ScholarPubMed
Moreira, ALR, Van Meter, A, Genzlinger, J, Youngstrom, EA Review and meta-analysis of epidemiologic studies of adult bipolar disorder. J Clin Psychiatry 2017; 78(9): e1259–69.CrossRefGoogle Scholar
Thornicroft, G, Chatterji, S, Evans-Lacko, S, Gruber, M, Sampson, N, Aguilar-Gaxiola, S, et al. Undertreatment of people with major depressive disorder in 21 countries. Br J Psychiatry 2017; 210(2): 119–24.CrossRefGoogle ScholarPubMed
Hayes, JF, Miles, J, Walters, K, King, M, Osborn, DPJ A systematic review and meta-analysis of premature mortality in bipolar affective disorder. Acta Psychiat Scand 2015; 131(6): 417–25.CrossRefGoogle ScholarPubMed
Ge, F, Huo, Z, Wen, Y. Incidence trends of major depressive disorder in 204 countries and territories between 1993 and 2017. J Affect Disord 2022; 296: 241–3.CrossRefGoogle ScholarPubMed
Hankin, BL, Abramson, LY, Moffitt, TE, Silva, PA, McGee, R, Angell, KE Development of depression from preadolescence to young adulthood: emerging gender differences in a 10-year longitudinal study. J Abnorm Psychol 1998; 107(1): 128–40.CrossRefGoogle Scholar
Luz, PM, Jalil, EM, Castilho, J, Velasque, L, Ramos, M, Ferreira, ACG, et al. Association of discrimination, violence, and resilience with depressive symptoms among transgender women in Rio de Janeiro, Brazil: a cross-sectional analysis. Transgen Health 2022; 7(1): 101–6.CrossRefGoogle Scholar
Scott, KM. Sex differences in the disability associated with mental disorders. Curr Opin Psychiatr 2011; 24(4): 331–5.CrossRefGoogle ScholarPubMed
Shuman, CJ, Peahl, AF, Pareddy, N, Morgan, ME, Chiangong, J, Veliz, PT, et al. Postpartum depression and associated risk factors during the COVID-19 pandemic. BMC Res Notes 2022; 15(1): 102.CrossRefGoogle ScholarPubMed
Akister, J, Owens, M, Goodyer, IM. Leaving care and mental health: outcomes for children in out-of-home care during the transition to adulthood. Health Res Policy Sy 2010; 8: 10.CrossRefGoogle ScholarPubMed
O'Connor, RC, Wetherall, K, Cleare, S, McClelland, H, Melson, AJ, Niedzwiedz, CL, et al. Mental health and well-being during the COVID-19 pandemic: longitudinal analyses of adults in the UK COVID-19 mental health & wellbeing study. Br J Psychiatry 2021; 218(6): 326–33.CrossRefGoogle ScholarPubMed
Mahdavinoor, SMM, Rafiei, MH, Mahdavinoor, SH. Mental health status of students during coronavirus pandemic outbreak: a cross-sectional study. Ann Med Surgery 2022; 78: 103739.CrossRefGoogle ScholarPubMed
Pitchforth, J, Fahy, K, Ford, T, Wolpert, M, Viner, RM, Hargreaves, DS Mental health and well-being trends among children and young people in the UK, 1995–2014: analysis of repeated cross-sectional national health surveys. Psychol Med 2019; 49(8): 1275–85.CrossRefGoogle Scholar
Odgers, CL, Jensen, MR. Annual research review: adolescent mental health in the digital age: facts, fears, and future directions. J Child Psychol Psychiatry 2020; 61(3): 336–48.CrossRefGoogle ScholarPubMed
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