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The Association Between Triple X and Psychosis

Published online by Cambridge University Press:  02 January 2018

Wendy J. Woodhouse ,
Anthony J. Holland ,
Greg McLean  and
Adrianne M. Reveley
Wendy J. Woodhouse*
Affiliation:
Bethlem Royal and Maudsley Hospitals, Denmark Hill, London SE5 8AZ
Anthony J. Holland
Affiliation:
Bethlem Royal and Maudsley Hospitals, and the Institute of Psychiatry, London
Greg McLean
Affiliation:
South Hants General Hospital, Southampton
Adrianne M. Reveley
Affiliation:
Bethlem Royal and Maudsley Hospitals
*
∗Correspondence
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Abstract

Two cases of psychotic illness in association with the karyotype triple X showed specific diagnostic and management problems as well as obstetric complications, EEG abnormalities, and lack of a family history of psychiatric disorder. Routine karyotyping during the investigation of psychosis is becoming relevant to psychiatric practice as research reports increasingly feature genetic and chromosome anomalies in association with schizophrenic psychoses.

British Journal of Psychiatry (1992), 160, 554–557

Type
Brief Reports
Information
The British Journal of Psychiatry , Volume 160 , Issue 4 , April 1992 , pp. 554 - 557
Copyright
Copyright © Royal College of Psychiatrists, 1992 

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References

American Psychiatric Association (1987) Diagnostic and Statistical Manual of Mental Disorders (3rd edn, revised) (DSM–III–R). Washington, DC: APA.Google Scholar
Bassett, A. S., McGilliveray, B. C., Jones, B. D., et al (1988) Partial trisomy chromosome 5 cosegregating with schizophrenia. Lancet, i, 799–800.Google Scholar
Crow, T. J. (1990) The continuum of psychosis and its genetic origins. British Journal of Psychiatry, 156, 788–797.CrossRefGoogle ScholarPubMed
Eagles, J. M., Gibson, I., Bremner, M. H., et al (1990) Obstetric complications in DSM–III schizophrenics and their siblings. Lancet, 335, 1139–1141.Google Scholar
Gershon, E. S., Targum, S. D., Mathysse, S., et al (1979) Colour blindness not closely linked to bipolar illness. Archives of General Psychiatry, 36, 1423–1430.Google Scholar
Gualtieri, C. T., Alexandra Adams, D. S. & Loiselle, D. (1982) Minor physical anomalies in alcoholic and schizophrenic adults and hyperactive and autistic children. American Journal of Psychiatry, 139, 540–643.Google Scholar
Holland, A. J. & Godsen, C. (1990) A balanced chromosomal translocation partially co-segregating with psychotic illness in a family. Psychiatric Research, 32, 1–8.Google Scholar
Johnstone, E. C., Crow, T. J., Frith, C. D., et al (1976) Cerebral ventricle size and cognitive impairment in chronic schizophrenia. Lancet, ii, 924–926.Google Scholar
Kidd, C. B., Knox, R. S., Mantle, D. J. (1963) A psychiatric investigation of triple-X chromosome females. British Journal of Psychiatry, 109, 90–94.Google Scholar
Olanders, S. (1967) Double barr bodies in women in mental hospitals. British Journal of Psychiatry, 113, 1097–1099.Google Scholar
Polani, P. E. (1977) Abnormal sex chromosomes, behaviour and mental disorder. In Developments in Psychiatric Research (ed. Tanner, J. M.), pp. 89–128. London: Hodder & Stoughton.Google Scholar
St Clair, D., Blackwood, D., Muir, W., et al (1990) Association within a family of a balanced autosomal translocation with major mental illness. Lancet, 336, 13–16.Google Scholar
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