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Clonidine

An Effective Anti-manic Agent?

Published online by Cambridge University Press:  02 January 2018

J. Maguire  and
A. N. Singh
J. Maguire*
Affiliation:
St Brigid's Hospital, Ardee, Eire
*
∗Correspondence
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Abstract

Three patients suffering from bipolar affective disorder, manic phase, and who were resistant to conservative treatment were successfully treated with clonidine. This would support the nor-adrenergic hyperactivity theory of mania. The rapidity of action of clonidine and its lack of relatively serious side-effects renders it a potential alternative to conventional anti-manic agents.

Type
Brief Reports
Information
The British Journal of Psychiatry , Volume 150 , Issue 6 , June 1987 , pp. 863 - 864
Copyright
Copyright © 1987 The Royal College of Psychiatrists 

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References

Farsang, C., Kunos, G. (1979) Naloxone reverses anti-hypertensive effect of clonidinc. British Journal of Pharmacology, 67, 161–164.CrossRefGoogle Scholar
Giannini, A. J., Exetein, I., Gold, M. S., Pottash, A. L. C. & Castellani, S. (1983) Clonidinc in mania, Drug development research. 3, 101–103.Google Scholar
Hoehn-Sarie, R., Merchant, A. F., Keyser, M. L. & Smyth, V. K. (1981) Effects of clonidine on anxiety disorders. Archives of General Psychiatry, 38, 1278–1282.Google Scholar
Lloyd, G. F. (1985) Emotional aspects of physical illness. In Recent Advances in Clinical Psychiatry, ed. Granville-Grossman, K. Edinburgh: Churchill Livingstone.Google Scholar
Schildkraut, J. J. (1978) Current status of the catecholamine hypothesis of affective disorders. In Psychopharmacology: A Generation of Progress, ed. Litpon, M. A., Di Mascio, A. & Killam, R. F. New York: Raven Press.Google Scholar
Zubenko, G. S., Cohen, B. M., Lipinski, J. F. & Jones, J. M. (1984) Clonidine in the treatment of mania and mixed bi-polar disorder. American Journal of Psychiatry, 141, 1617–1618.Google Scholar
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