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An Ion Source for the HVEE 14C Isotope Ratio Mass Spectrometer for Biomedical Applications

Published online by Cambridge University Press:  18 July 2016

Dirk J. W. Mous
Affiliation:
High Voltage Engineering Europa B.V., PO Box 99, 3800 AB Amersfoort, The Netherlands
Wim Fokker
Affiliation:
High Voltage Engineering Europa B.V., PO Box 99, 3800 AB Amersfoort, The Netherlands
Rein Van Den Broek
Affiliation:
High Voltage Engineering Europa B.V., PO Box 99, 3800 AB Amersfoort, The Netherlands
Ron Koopmans
Affiliation:
High Voltage Engineering Europa B.V., PO Box 99, 3800 AB Amersfoort, The Netherlands
Christopher Bronk Ramsey*
Affiliation:
Oxford Radiocarbon Accelerator Unit, Oxford University, 6 Keble Road, Oxford 0X1 3QJ United Kingdom
R. E. M. Hedges*
Affiliation:
Oxford Radiocarbon Accelerator Unit, Oxford University, 6 Keble Road, Oxford 0X1 3QJ United Kingdom
*
1These authors were exclusively involved in the design and development of the CO2 ion source.
1These authors were exclusively involved in the design and development of the CO2 ion source.
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Abstract

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During the past two decades, accelerator mass spectrometry (AMS) has allowed major developments in many areas of geosciences and archaeology. In the near future, AMS should realize a similar potential in the field of biomedical research, leading ultimately to clinical applications. For such applications, the required instrument differs significantly from that presently used in the field of 14C dating. Whereas the needed accuracy and sensitivity is more than an order of magnitude less demanding than that for present state-of-the-art 14C instrumentation, the widespread acceptance of 14C AMS in biomedical research will require AMS spectrometers that are small, simple to operate and capable of handling CO2 samples. In order to satisfy these demands, HVEE has developed a compact 14C AMS spectrometer dedicated to biomedical research. The instrument consists of a compact accelerator with a footprint of 2.25 × 1.25 m and an ion source that features direct CO2 acceptance and optimal user friendliness. Having previously described the layout and design of the accelerator, we here discuss progress on the accelerator and present the design and first results of the CO2 ion source.

Type
Part 1: Methods
Copyright
Copyright © The American Journal of Science 

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