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Biological and model membranes studied by nuclear magnetic resonance of spin one half nuclei

Published online by Cambridge University Press:  17 March 2009

Håkan Wennerström  and
Göran Lindblom
Håkan Wennerström
Affiliation:
Division of Physical Chemistry 2, Chemical Centre, P.O.B. 740, S-220 07 Lund 7, Sweden
Göran Lindblom
Affiliation:
Division of Physical Chemistry 2, Chemical Centre, P.O.B. 740, S-220 07 Lund 7, Sweden
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Extract

There is an inherent anisotropy in biological and model membrane systems and this anisotropy has a profound influence on the nuclear magnetic resonance spectra of such systems. For nuclei with a quadrupole moment the quadrupole coupling usually dominates the NMR spectrum, while for nuclei with spin quantum number I = ½ dipolar couplings provides the most important effects. The quadrupole coupling only affects isolated spins and usually gives rise to simple spectra. The dipole interactions on the other hand couple several spins. In a lipid bilayer with a multitude of spin-½ nuclei these couplings can give rise to complicated manybody effects. Thus the interpretation of the NMR spectra of membrane systems poses problems but at the same time there is a lot of information to be gained.

Type
Research Article
Information
Quarterly Reviews of Biophysics , Volume 10 , Issue 1 , February 1977 , pp. 67 - 96
Copyright
Copyright © Cambridge University Press 1977

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