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Life-events and psychiatric disorders1 Part 1: some methodological issues

Published online by Cambridge University Press:  09 July 2009

G. W. Brown
Affiliation:
From the Department of Sociology, Bedford College, University of London
F. Sklair
Affiliation:
From the Department of Sociology, Bedford College, University of London
T. O. Harris
Affiliation:
From the Department of Sociology, Bedford College, University of London
J. L. T. Birley
Affiliation:
Institute of Psychiatry, University of London

Synopsis

The paper focuses on recent criticisms of the study of the role of life-events in the onset of psychiatric conditions and suggests that measurement error and bias can be reasonably well controlled by various methodological procedures. Failure to comply with these may be expected, however, to increase rather than decrease the chances of establishing a ‘positive’ resuit. Three further factors to do with the design of studies and the analysis of data are discussed which are likely to mask real differences between patient and comparison group, and which therefore might explain the ‘negative’ results reported in the literature. They concern: (1) the choice of an appropriate comparison group; (2) specification of the length of the period between event and onset; and (3) specification of the event in terms of some measure of severity. Results from two London studies of schizophrenic and depressive patients are presented to illustrate the argument. The studies suggest that life-events do play an important causal role in bringing about both disorders.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1973

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