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The benzodiazepines: recent trends1

Published online by Cambridge University Press:  09 July 2009

I. L. Martin
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Abstract

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Type
Editorial
Information
Psychological Medicine , Volume 12 , Issue 4 , November 1982 , pp. 689 - 693
Copyright
Copyright © Cambridge University Press 1982

References

Ban, T. A., Brown, W. T., Da, Silva T., Gagnon, M. A., Lamont, H. E., Leeman, H. E., Lowy, F. W., Rudey, J., & Sellers, E. M. (1981). Therapeutic monograph on anxiolytic–sedative drugs. Canadian Pharmaceutical Journal 114, 301–308.Google Scholar
Braestrup, C., Nielsen, M. & Olesen, C. E. (1980). Urinary and brain βcarboline-3-carboxylates as potent inhibitors of brain benzodiazepine receptors. Proceedings of the National Academy of Sciences (USA) 77, 2288–2292.CrossRefGoogle ScholarPubMed
Brown, C. L. & Johnson, A. M. (1982). Ethyl β-carboline-3-carboxylate reverses the effects of benzodiazepines in a test for detecting anxiolytic activity. British Journal of Pharmacology 75, 43P.Google Scholar
Cowan, P. J., Green, A. R., Nutt, D. J. & Martin, I. L. (1981). Ethyl β-carboline carboxylate lowers seizure threshold and antagonises flurazepam induced sedation in rats. Nature 290 54–55.CrossRefGoogle Scholar
Czernik, A. J., Petrack, B., Tsai, C., Granat, R. F., Rinehart, R. K., Kalinsky, H. J., Lovell, R. A. & Cash, W. D. (1981). High affinity occupancy of benzodiazepine receptors by the novel antagonist CGS-8216. Pharmacologist 23, 160.Google Scholar
Davis, N. M., Brookes, S., Gray, J. A. & Rawlins, J. N. P. (1981). Chlorodiazepoxide and resistance to punishment. Quarterly Journal of Experimental Psychology 33B, 227–239.CrossRefGoogle Scholar
Doble, A., Iversen, L. L. & Martin, I. L. (1982 a). The benzodiazepine binding site: one receptor or two. British Journal of Pharmacology 75, 42P.Google Scholar
Doble, A., Martin, I. L. & Richards, D. A. (1982 b). GABA modulation predicts biological activity of ligands for the benzodiazepine receptor. British Journal of Pharmacology 76, 238P.Google Scholar
Hunkeler, W., Möhler, H., Pieri, L., Polc, P., Bonetti, E. P., Cumin, R., Schaffner, R. & Haefely, W. (1981). Selective antagonists of benzodiazepines. Nature 290. 514–516.CrossRefGoogle ScholarPubMed
Jones, B. J. & Oakley, N. R. (1981). The convulsant properties of methyl β-carboline-3-carboxylate in the mouse. British Journal of Pharmacology 74, 884P.Google Scholar
Martin, I. L. (1980). Endogenous ligands for benzodiazepine receptors. Trends in Neurosciences 3, 299–301.CrossRefGoogle Scholar
Möhler, H. (1981). Benzodiazepine receptors: are there endogenous ligands in the brain? Trends in Pharmacological Sciences 1, 116–119.CrossRefGoogle Scholar
Möhler, H. & Okada, T. (1977). Benzodiazepine receptor:demonstration in the central nervous system. Science 198, 849–851.CrossRefGoogle ScholarPubMed
Nielsen, M. & Braestrup, C. (1980). Ethyl β-carboline-3-carboxylate shows differential benzodiazcpine receptor interaction. Nature 286, 606–607.CrossRefGoogle ScholarPubMed
Nutt, D. J., Cowan, P. J. & Little, H. J. (1982). Unusual interactions of benzodiazepine receptor antagonists. Nature 295, 436–438.CrossRefGoogle ScholarPubMed
Oakley, N. R. & Jones, B. J. (1980). The proconvulsant and diazepam reversing effects of ethyl β-carboline-3-carboxylate. European Journal of Pharmacology 68, 381–382.CrossRefGoogle ScholarPubMed
Squires, R. F. & Braestrup, C. (1977). Benzodiazepine receptors in rat brain. Nature 266, 732–734.CrossRefGoogle ScholarPubMed
Squires, R. F., Benson, D. I., Braestrup, C., Coupet, J., Klepner, C. A., Myers, V. & Beer, B. (1979). Some properties of brain specific benzodiazepine receptors: new evidence for multiple receptors. Pharmacology, Biochemistry and Behoviour 10, 825–830.CrossRefGoogle ScholarPubMed
Tenen, S. S. & Hirsch, J. D. (1980). Antagonism of diazepam activity by β-carboline-3-carboxylic acid ethyl ester. Nature 288, 609–610.CrossRefGoogle ScholarPubMed
Woolf, J. H. & Nixon, J. C. (1981). Endogenous effector of the benzodiazepine binding site: purification and characterisation. Biochemistry 20, 4263–4269.CrossRefGoogle Scholar