Hostname: page-component-7479d7b7d-pfhbr Total loading time: 0 Render date: 2024-07-11T06:09:37.588Z Has data issue: false hasContentIssue false
  • English
  • Français

Agenesis of the corpus callosum and schizophrenia: a case report

Published online by Cambridge University Press:  09 July 2009

S. W. Lewis ,
M. A. Reveley ,
A. S. David  and
M. A. Ron
S. W. Lewis*
Affiliation:
Institute of Psychiatry; Department of Psychiatry, The London Hospital; Maudsley Hospital; Department of Psychiatry, The National Hospital for Nervous Diseases, London
M. A. Reveley
Affiliation:
Institute of Psychiatry; Department of Psychiatry, The London Hospital; Maudsley Hospital; Department of Psychiatry, The National Hospital for Nervous Diseases, London
A. S. David
Affiliation:
Institute of Psychiatry; Department of Psychiatry, The London Hospital; Maudsley Hospital; Department of Psychiatry, The National Hospital for Nervous Diseases, London
M. A. Ron
Affiliation:
Institute of Psychiatry; Department of Psychiatry, The London Hospital; Maudsley Hospital; Department of Psychiatry, The National Hospital for Nervous Diseases, London
*
1Address for correspondence: Dr S. W. Lewis. Institute of Psychiatry, De Crespigny Park, London SE5 8AF.
Get access Rights & Permissions [Opens in a new window]

Synopsis

Clinical, radiological and neuropsychological findings in the first reported case of schizophrenia with complete agenesis of the corpus callosum are described. Although causal inferences were made difficult by the co-existence of a left frontotemporal cyst and a family history of affective disorder, some theories of the role of callosal dysfunction in schizophrenia require revision in the light of this case.

Type
Research Article
Information
Psychological Medicine , Volume 18 , Issue 2 , May 1988 , pp. 341 - 347
Copyright
Copyright © Cambridge University Press 1988

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Andermann, E. (1981). Agenesis of the corpus callosum. In Handbook of Clinical Neurology, Vol. 42 (ed. Vinken, P. J. and Bruyn, G. W.), pp. 6–9North Holland: Amsterdam.Google Scholar
Beaumont, J. G. & Dimond, S. J. (1973). Brain disconnection and schizophrenia. British Journal of Psychiatry 123, 661–662.CrossRefGoogle ScholarPubMed
Bigelow, L. B., Nasrallah, H. A. & Rauscher, F. P. (1983). Corpus callosum thickness in chronic schizophrenia. British Journal of Psychiatry 142, 284–287.CrossRefGoogle ScholarPubMed
Brown, R., Colter, N., Corsellis, J. A. N., Crow, T. J., Frith, C. D., Jagoe, R., Johnstone, E. C. & Marsh, L. (1986). Postmortem evidence of structural brain changes in schizophrenia. Archives of General Psychiatry 43, 36–42.CrossRefGoogle ScholarPubMed
Carr, S. A. (1980). Interhemispheric transfer of stereognostic information in chronic schizophrenics British Journal of Psychiatry 136, 53–58.CrossRefGoogle ScholarPubMed
Chiarello, C. (1980). A house divided? Cognitive functioning with callosal agenesis. Brain and Language 11, 128–158.CrossRefGoogle ScholarPubMed
Cronin-Golomb, A. (1986). Subcortical transfer of cognitive information in subjects with complete forebrain commissurotomy. Cortex 22, 499–519.CrossRefGoogle ScholarPubMed
David, A. S. (1987). Tachistoscopic tests of colour naming and matching in schizophrenia. Evidence of posterior callosum dysfunction? Psychological Medicine 17, 621–630.CrossRefGoogle ScholarPubMed
Dennis, M. (1976). Impaired sensory and motor differentiation with corpus callosum agenesis: a lack of callosal inhibition during ontogeny? Neuropsychologia 14, 455–469.CrossRefGoogle ScholarPubMed
Dimond, S. J., Scammell, R., Pryce, I. J., Huws, D. & Gray, C. (1980). Some failures of intermanual and cross-lateral transfer in chronic schizophrenia. Journal of Abnormal Psychology 89, 505–509.CrossRefGoogle ScholarPubMed
Elliott, F. A. (1969). The corpus callosum, cingulate gyrus, septum pellucidum, septal area and fornix. In Handbook of Clinical Neurology, Vol. 2 (ed. Vinken, P J. and Bruyn, G. W.), pp. 758–775. North Holland: Amsterdam.Google Scholar
Green, P. (1978). Defective interhemispheric transfer in schizophrenia. Journal of Abnormal Psychology 87, 472–480.CrossRefGoogle ScholarPubMed
Gulmann, N. C., Wildschiodtz, G. & Orbaek, K. (1982). Alteration of interhemisphere conduction through corpus callosum in chronic schizophrenia. Biological Psychiatry 17, 585–594.Google ScholarPubMed
Hatta, T., Yamamoto, M. & Kawabata, Y. (1984). Functional hemispheric differences in schizophrenia: interhemispheric transfer deficit or selective hemisphere dysfunction? Biological Psychiatry 19, 1027–1036.Google ScholarPubMed
Jeeves, M. A. (1984). Functional and neuronal plasticity: the evidence from callosal agenesis In Early Brain Damage Vol. I (ed. Almli, C. R. and Finger, S.), pp. 233–252. Academic Press: Orlando.CrossRefGoogle Scholar
Johnson, M. H. & Jones, S. N (1985). Status epilepticus, hypothermia and metabolic chaos in a man with agenesis of the corpus callosum. Journal of Neurology, Neurosurgery and Psychiatry 48, 480–483.CrossRefGoogle Scholar
Jones, G. H. & Miller, J. J. (1981). Functional tests of the corpus callosum in schizophrenia. British Journal of Psychiatry 139, 553–557.CrossRefGoogle ScholarPubMed
Kendall, B. E. (1983). Dysgenesis of the corpus callosum. Neuroradiology 25, 239–256.CrossRefGoogle ScholarPubMed
Kobori, J. A, Herrick, M. K. & Urich, H. (1987). Arhinoencephaly. The spectrum of associated malformations. Brain 110, 237–260.CrossRefGoogle ScholarPubMed
Lynn, R. B., Buchanan, D. C, Fenichel, G. M. & Freemon, F. R. (1980). Agenesis of the corpus callosum. Archives of Neurology 37, 444–445.CrossRefGoogle ScholarPubMed
Mathew, R. J., Partain, C L.Prakash, R., Kulkarni, M. V., Logan, T. P. & Wilson, W. H (1985). A study of the septum pellucidum and corpus callosum in schizophrenia with MR imaging. Acta Psychiatrica Scandinavica 72, 414–421.CrossRefGoogle ScholarPubMed
Menkes, J. H., Philippart, M. & Clark, D. B. (1964). Hereditary partial agenesis of corpus callosum. Archives of Neurology 11, 198–208.CrossRefGoogle ScholarPubMed
Merriam, A. E. & Gardner, E. B. (1987). Corpus callosum function in schizophrenia: a neuropsychological assessment of interhemispheric information processing. Neuropsychologia 25, 185–193.CrossRefGoogle ScholarPubMed
Milner, D. (1983). Neuropsychological studies of callosal agenesis Psychological Medicine 13, 721–725.CrossRefGoogle ScholarPubMed
Moniz, E. (1927). Les tumeurs du corps calleux. Encéphale 22, 514–532.Google Scholar
Nasrallah, H. A. (1982). Laterality and hemispheric dysfunction in schizophrenia. In Schizophrenia as a Brain Disease (ed. Henn, F. A. and Nasrallah, H. A.), pp. 273–294. Oxford University Press: New YorkGoogle Scholar
Nasrallah, H. A., Andreasen, N. C., Coffman, J. A., Olson, S. C., Dunn, V. D., Ehrhardt, J. C. & Chapman, S. M. (1986). A controlled magnetic resonance imaging study of corpus callosum thickness in schizophrenia. Biological Psychiatry 21, 274–282.CrossRefGoogle ScholarPubMed
Rakic, P. & Yakovlev, P. I. (1968). Development of the corpus callosum and cavum septi in man. Journal of Comparative Neurology 132, 45–72.CrossRefGoogle ScholarPubMed
Rosenthal, R. & Bigelow, L. B. (1972). Quantitative brain measurements in chronic schizophrenia. British Journal of Psychiatry 121, 259–264.CrossRefGoogle ScholarPubMed
Sauerwein, H. & Lassonde, M. C. (1983). Intra- and interhemispheric processing of visual information in callosal agenesis. Neuropsychologia 21, 167–171.CrossRefGoogle ScholarPubMed
Shagass, C., Josiassen, R. C., Roemer, R. A, Straumanis, J. J. & Slepner, S. M. (1983) Failure to replicate evoked potential observations suggesting corpus callosum dysfunction in schizophrenia. British Journal of Psychiatry 142, 471–476.CrossRefGoogle ScholarPubMed
Sperry, R. W., Gazzaniga, M. S. & Bogen, J. E. (1969). Interhemispheric relationships: the neocortical commissures, syndromes of hemisphere disconnection. In Handbook of Clinical Neurology, Vol. 4 (ed. Vinken, P. J. and Bruyn, G. W.), pp 273–290. North Holland: Amsterdam.Google Scholar
Tress, K. H, Kugler, B. T. & Caudrey, D. J (1979). Interhemispheric integration in schizophrenia. In Hemisphere Asymmetries of Function in Psychopathology (ed. Gruzelier, J. and Flor-Henry, P.), pp. 449–462. Elsevier: Amsterdam.Google Scholar
Walker, E. & McGuire, M. (1982) Intra- and interhemispheric information processing on schizophrenia. Psychological Bulletin 12, 701–725.CrossRefGoogle Scholar
Walker, E., Hoppes, E. & Emory, E. (1981). A reinterpretation of findings on hemispheric dysfunction in schizophrenia. Journal of Nervous and Mental Disease 169, 378–380.CrossRefGoogle ScholarPubMed