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Behaviour of the Ring-Chromosome in Drosophila Melanogaster*

Published online by Cambridge University Press:  11 June 2012

P. Battacharya
P. Battacharya
Affiliation:
Institute of Animal Genetics, University of Edinburgh
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Synopis

The genetical studies on ring-chromosomes in Drosophila show that there is no interlocking of chromatids at mitosis.

Dicentric ring-chromosomes formed at meiosis on being pulled apart do not become broken with subsequent reunion of the broken ends. This may be due to the failure of these chromosomes either to rejoin or to become broken at all.

The results make it probable that there is a gene or genes located in one of chromocentral regions of the X-chromosome of Drosophila, probably in the region at the distal end, which has a function in ensuring the orderly segregation of the chromatids in the early cleavage stages of the fertilised eggs. Hence the absence of this chromosome region results in a tendency to gynandromorphism.

Results indicate the incorrectness of the view that the inviable zygotes and the patroclinous males found in the ring-chromosome stock arise from different kinds of eggs (single cross-over and progressive double cross-over respectively, as proposed by L. V. Morgan). Both arise from eggs that have for any reason failed to receive a monocentric X-chromosome. This result occurs in all cases of digressive double crossing-over and in half the cases of progressive double crossing-over. Such virtually X-less eggs, when fertilised by an X-bearing sperm, form patroclinous males, and when fertilised by a Y-bearing sperm, form inviable zygotes. The classes thus found are therefore equal in number.

Type
Research Article
Information
Proceedings of the Royal Society of Edinburgh, Section B: Biological Sciences , Volume 64 , Issue 2 , 1950 , pp. 199 - 215
Copyright
Copyright © Royal Society of Edinburgh 1950

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Footnotes

*

This paper was assisted in publication by a grant from the Carnegie Trust for the Universities of Scotland.

References

References to Literature

Beadle, G. W., 1934. “Crossing-over in Attached X-Triploids of Drosophila melanogaster”, Journ. Genet., xxix, 277–309.CrossRefGoogle Scholar
Beadle, G. W., and Sturtevant, A. H., 1935. “X-Chromosome Inversions and Meiosis in Drosophila melanogaster”, Proc. Nat. Acad. Sci. Wash., xxi, 384–390.CrossRefGoogle Scholar
Darlington, C. D., 1937. Recent Advances in Cytology, 2nd ed., J. A. Churchill Ltd., London.Google Scholar
McClintock, Barbara, 1932. “A Correlation of Ring-shaped Chromosomes with Variegation in Zea mays”, Proc. Nat. Acad. Sci. Wash., XVIII, 677–681.CrossRefGoogle Scholar
Morgan, L. V., 1926. “Correlation between Shape and Behaviour of a Chromosome“, Proc. Nat. Acad. Sci. Wash., xii, 180–181.CrossRefGoogle Scholar
Morgan, L. V., 1929. “Composites of Drosophila melanogaster“, Publ. Carneg. Inst. Wash., No. 399, 223–296.Google Scholar
Morgan, L. V., 1932. “Genetic Behaviour of a Closed X-Chromosome of Drosophila“, Proc. 6th Internat. Cong. Genet., 11, 135–137.Google Scholar
Morgan, L. V., 1933. “A Closed X-Chromosome in Drosophila melanogaster“, Genetics, xviii, 250–283.CrossRefGoogle Scholar
Muller, H. J., and Settles, F., 1926. “The Non-functioning of the Genes in Spermatozoa“, Zeits. f. Ind. Abst. u. Vererb., XLIII, 285–312.Google Scholar
Navashin, M., 1930. “Unbalanced Somatic Chromosomal Variation in Crepis“, Univ. Calif. Publ. Agric. Sci., vi, 3, 95–106.Google Scholar
Prokofyeva-Belgovskaya, A. A., 1937. “Inert Regions in the Distal Ends of Chromosomes of Drosophila melanogaster“, Bull. I'Acad. Sci. U.R.S.S., 719–723; English Summary, 723–724.Google Scholar
Rhoades, M. M., and McClintock, Barbara, 1935. “The Cytogenetics of Maize“, Bot. Rev., 1, 292–325.CrossRefGoogle Scholar
Schultz, Jack, and Catcheside, D. G., 1937. “The Nature of Closed X-Chromosomes in Drosophila melanogaster“, Journ. Genet., xxxv, 2,Google Scholar
Sidorov, B. P., Sokolov, N. N., and Trofimov, I. E., 1935. “Forces of Attraction of Homologous Loci and Chromosome Conjugation“, Nature, cxxxvi, 108–109.CrossRefGoogle Scholar
Sidorov, B. P., Sokolov, N. N., and Trofimov, I. E., 1936. “Crossing-over in Heterozygoten Inversionen“, Genetica, xviii, 291–312.CrossRefGoogle Scholar
Sturtevant, A. H., and Beadle, G. W., 1936. “The Relations of Inversions in the X-Chromosome of Drosophila melanogaster to Crossing-over and Disjunction“, Genetics, xxi, 554–604.CrossRefGoogle Scholar
Upcott, Margaret, 1937. “The Genetic Structure of Tulipa“, Journ. Genet., xxxiv, 339–398.CrossRefGoogle Scholar
White, M. J. D., 1935. “The Effect of X-rays on Mitosis in the Spermatogonial Divisions of Locusta migratoria“, Proc. Roy. Soc, B, cxix, 61–84.Google Scholar