Hostname: page-component-848d4c4894-v5vhk Total loading time: 0 Render date: 2024-06-27T15:27:22.245Z Has data issue: false hasContentIssue false
  • English
  • Français

Leucocyte sub-sets and acute phase proteins are associated with productivity in Large White pigs

Published online by Cambridge University Press:  20 November 2017

M. Clapperton ,
S.C. Bishop  and
E.J. Glass
M. Clapperton*
Affiliation:
Roslin Institute (Edinburgh), Roslin, Midlothian EH25 9PS.
S.C. Bishop
Affiliation:
Roslin Institute (Edinburgh), Roslin, Midlothian EH25 9PS.
E.J. Glass
Affiliation:
Roslin Institute (Edinburgh), Roslin, Midlothian EH25 9PS.
*
Email: Mary.Clapperton@bbsrc.ac.uk
Get access

Extract

The exposure of pigs to different pathogens compromises productivity, i.e. reduces weight gain and food intake (Balaji et al., 2000; Greiner et al., 2000), even in the absence of clinical disease. Infection also often causes the release of acute phase proteins and the proliferation of certain leucocyte subsets (Baumann and Gauldie, 1994; Licence and Binns, 1995). Therefore, it may be hypothesised that associations should exist between productivity and a range of immunological traits in apparently-healthy animals facing the same infectious challenge. This would be important in pigs suffering sub-clinical infections, as it would enable predictions of health status and effects of infection on performance. This study investigated such associations in apparently-healthy pigs facing unknown subclinical challenges.

Type
ISAE
Information
Proceedings of the British Society of Animal Science , Volume 2003 , 2003 , pp. 32
Copyright
Copyright © The British Society of Animal Science 2003

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Balaji, R., Wright, K.J., Hill, D.M., Knoppel, E.L. and Minton, J.E. 2000. Acute phase responses of pigs challenged orally with Salmonella typhimurium. Journal of Animal Science 78: 1885–1891.CrossRefGoogle ScholarPubMed
Baumann, H., and Gauldie, J. 1994. The acute phase response. Immunology Today 15: 74–80.Google Scholar
Greiner, L.L., Stahly, T.S. and Stabel, J.J. 2000. Quantitative relationship of systemic virus concentration on growth and immune response in pigs. Journal of Animal Science 78: 2690–2695.CrossRefGoogle ScholarPubMed
Licence, S.T., and Binns, R.M. 1995. Major long-term changes in gamma delta T-cell receptor positive and CD2+ T-cell subsets after neonatal thymectomy in the pig: a longitudinal study lasting nearly 2 years. Immunology 85: 276–284.Google ScholarPubMed