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Changes in the gene expression of progesterone receptor and prolactin receptor in sow mammary gland between late gestation and lactation

Published online by Cambridge University Press:  05 November 2021

H. M. Miller
Affiliation:
Department of Animal Physiology and Nutrition, University of Leeds, Leeds, LS2 9JT
W. T. Dixon
Affiliation:
Department of Agriculture, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada.
G. R. Foxcroft
Affiliation:
Department of Agriculture, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada.
F. X. Aherne
Affiliation:
Department of Agriculture, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada.
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Extract

Lactogenesis is triggered by a rapid decline in plasma progesterone concentration combined with a peak in plasma prolactin concentration; in mice, there is a concurrent loss of mammary progesterone receptors (Haslam and Shyamala, 1980). The aims of this experiment were to determine the pattern of change of progesterone receptor and prolactin receptor mRNA during late gestation and early lactation and to determine whether abundance of mRNA for the two receptors are related to each other, to plasma concentrations of progesterone and prolactin or to piglet performance.

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Programme
Copyright
Copyright © The British Society of Animal Science 1998

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References

Djiane, J. and Durand, P. (1977) Prolactin-progesterone antagonism in self regulation of prolactin receptors in the mammary gland. Nature, 266, 641643.10.1038/266641a0CrossRefGoogle ScholarPubMed
Hartmann, P.E. and Holmes, M.A (1989) Sow Lactation. In: Manipulating Pig Production II ed. Barnett, and Hennessy, , APSA, Werribee, Australia.Google Scholar
Haslem, S.Z. and Shyamala, G. (1980) Progesterone receptors in normal mammary gland: receptor modulations in relation to differentiation. The Journal of Cell Biology 86: 730737.10.1083/jcb.86.3.730CrossRefGoogle Scholar