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Covalently-linked Adducts of Single-walled Nanotubes with Biomolecules: Synthesis, Hybridization, and Biologically-Directed Surface Assembly

Published online by Cambridge University Press:  11 February 2011

Sarah E. Baker
Affiliation:
Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue Madison, WI 53706
Tami L. Lasseter
Affiliation:
Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue Madison, WI 53706
Lloyd M. Smith
Affiliation:
Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue Madison, WI 53706
Robert J. Hamers
Affiliation:
Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue Madison, WI 53706
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Abstract

Covalently-linked adducts of single-walled carbon nanotubes (SWNTs) with biomolecules have been fabricated. Results are presented here for DNA-SWNT and for biotin-SWNT adducts. DNA-SWNT adducts are shown to be biochemically accessible and to exhibit high selectivity, favoring hybridization with complementary vs. non-complementary DNA sequences. Biotin-SWNT adducts were also prepared and used to direct the assembly of nanotubes onto a biotinylated glass surface.

Type
Research Article
Copyright
Copyright © Materials Research Society 2003

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References

REFERENCES

Elghanian, R.; Storhoff, J. J.; Mucic, R. C.; Letsinger, R. L.; Mirkin, C. A. Science, 277, 1078, (1997).Google Scholar
[2] Perez, J. M.; O'Loughin, T.; Simeone, F. J.; Weissleder, R.; Josephson, L. J. Am. Chem. Soc., 124, 2856 (2002).Google Scholar
[3] Tsang, S. C.; Guo, Z.; Chen, Y. K.; Green, M. L. H.; Hill, H. A. O.; Hambley, T. W.; Sadler, P. J. Angew. Chem. Int. Ed. Engl., 36, 2198 (1998).Google Scholar
[4] Guo, Z.; Sadler, P. J.; Tsang, S. C. Adv. Mater., 10, 701 (1998).Google Scholar
[5] Chen, R. J.; Zhang, Y.; Wang, D.; Dai, H. J. Am. Chem. Soc., 123, 3838 (2001).Google Scholar
[6] Shim, M.; Kam, N. W. S.; Chen, R. J.; Li., Y.; Dai, H. Nano Letters, 2, 285 (2002).Google Scholar
[7] Baker, S. E.; Cai, W.; Lasseter, T. L.; Weidkamp, K. P.; Hamers, R. J. Nano Letters, 2, 1413 (2002).).Google Scholar
[8] Lasseter, T. L.; Baker, S. E.; Smith, L. M.; Hamers, R. J. In preparation (2002).Google Scholar
[9] Zhao, W.; Song, C.; Pehrsson, P. E. J. Am. Chem. Soc., 124, 12418 (2002).Google Scholar
[10] Strother, T.; Cai, W.; Zhao, X.; Hamers, R. J.; Smith, L. M. J. Am. Chem. Soc., 122 12051209 (2000).Google Scholar