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Cell Adhesion to Ion Implanted Titanium

Published online by Cambridge University Press:  26 February 2011

K. S. Grabowski ,
C. R. Gossett ,
F. A. Young  and
J. C. Keller
K. S. Grabowski
Affiliation:
Naval Research Laboratory, Code 4671, Washington, DC 20375-5000
C. R. Gossett
Affiliation:
Naval Research Laboratory, Code 4671, Washington, DC 20375-5000
F. A. Young
Affiliation:
Naval Research Laboratory, Code 4671, Washington, DC 20375-5000 Medical University of South Carolina, Dept. of Materials Science, 171 Ashley Ave., Charleston, SC 29425
J. C. Keller
Affiliation:
Naval Research Laboratory, Code 4671, Washington, DC 20375-5000 Medical University of South Carolina, Dept. of Materials Science, 171 Ashley Ave., Charleston, SC 29425
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Abstract

This preliminary investigation evaluates the influence of ion implantation on tissue adhesion by measuring the tendency of fibroblasts to attach to the surface of ion implanted Ti. For this work, polished specimens of commercially pure Ti were implanted with ions of Ti, Ca, C, or N to produce a surface concentration of the implanted element up to about 25 at. %. Unimplanted and ASTM treated Ti, and tissue culture plate specimens were prepared as controls. Specimens were sterilized, then exposed for 15 min. to a culture medium containing about 100,000 fibroblasts. The solution and loose fibroblasts were rinsed away and the fibroblasts counted to determine those left attached. The influence of the different implantation protocols on fibroblast adhesion to Ti will be described. Analysis of the structure and composition of the ion implanted surfaces was obtained by scanning electron microscopy, x-ray photoelectron spectroscopy, and elastic backscattering spectrometry of energetic He ions.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 110: Symposium M – Biomedical Materials and Devices , 1987 , 697
Copyright
Copyright © Materials Research Society 1988

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