Hostname: page-component-77c89778f8-sh8wx Total loading time: 0 Render date: 2024-07-21T03:37:03.375Z Has data issue: false hasContentIssue false
  • English
  • Français

Mechanical properties of stratum corneum studied by nano-indentation

Published online by Cambridge University Press:  11 February 2011

Yonghui Yuan  and
Ritu Verma
Yonghui Yuan
Affiliation:
Unilever Research, Edgewater, NJ, 07020
Ritu Verma
Affiliation:
Unilever Research, Edgewater, NJ, 07020
Get access

Abstract

Stratum corneum acts as a barrier to protect our body, as well as a pathway for conducting skin sensations. Understanding the mechanical properties such as elasticity, yield stress, of stratum corneum is important to improve and develop new products in the personal care industry. In this work, structural properties of stratum corneum are studied by atomic force microscopy (AFM) imaging to reveal surface structure of stratum corneum. To study mechanical properties, AFM force measurements and nano-indentation techniques were used to characterize elastic properties of dry and wet stratum corneum. Nano-DMA measurements were also conducted to characterize visco-elastic properties of the same material.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 738: Symposium G – Spatially Resolved Characterization of Local Phenomena in Materials and Nanostructures , 2002 , G10.2
Copyright
Copyright © Materials Research Society 2003

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

REFERENCES

Wu, K. S., Van Osdol, W. W., and Dauskardt, R. H., “Mechanical and microstructural properties of stratum corneum”, Proceedings of the Spring MRS Meeting, San Francisco, 2001.Google Scholar
2. Elsner, P., Berardesca, E., Wilhelm, K-P, and Maibach, H. I., “Bioengineering of the skin — skin biomechanics”, CRC Press, 2002.Google Scholar
3. Raju, B. I., and Srinivasan, M. A., “In vivo characterization of human fingertip and forearm skin using attenuation of high frequency ultrasound“, presented at the 2000 IEEE Ultrasonics Symposium, San Juan, Puerto Rico, Oct 2000.Google Scholar
4. Golder, G. M., Guzek, D.B., Kennedy, A. H., Mekie, J. E. and Potts, R.O., “Stratum corneum lipid phase transitions and water barrier properties”, Biochemistry, 1987, 26, 2382–2388.Google Scholar
5. Domke, J., and Radmacher, M., “Measuring the elastic properties of thin polymer films with the atomic force microscope”, Langmuir, 1998, 14, 3320–3325.Google Scholar
6. Elsner, P., Berardesca, E., and Maibach, H. I., “Bioengineering of the skin — water and the stratum corneum”, CRC Press, 1994.Google Scholar
7. Triboscope user's Manual, Hysitron.Google Scholar