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Synthesis of a thermo- and pH-sensitive comb-type graft copolymer by ionizing radiation

Published online by Cambridge University Press:  17 August 2018

Victor H. Pino-Ramos  and
Emilio Bucio
Victor H. Pino-Ramos*
Affiliation:
Departamento de Química de Radiaciones y Radioquímica, Instituto de Ciencias Nucleares, Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, CDMX 04510, México
Emilio Bucio
Affiliation:
Departamento de Química de Radiaciones y Radioquímica, Instituto de Ciencias Nucleares, Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, CDMX 04510, México
*
Address all correspondence to Victor H. Pino-Ramos at victor.pino@correo.nucleares.unam.mx
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Abstract

A thermo-pH sensitive graft copolymer was successfully obtained by grafting 4-vinylpyridine and N-vinylcaprolactam onto silicone rubber ((SR-g-4VP)-g-NVCL)) in two-step using ionizing radiation as an initiator. Factors such as dose and monomer concentration remarkably affected the grafting yield. Surface grafted films were well characterized by means of infrared-attenuated total reflection, carbon-13 nuclear magnetic resonance, thermogravimetric analysis, and mechanical properties were also studied. Scanning electron microscopy demonstrated that the grafting was superficial; mechanical studies demonstrated that grafting caused loss elongation of SR films. The grafted films showed a critical pH close to physiological pH and a critical temperature (lower critical solution temperature) about 35 °C, therefore, this material presents potential biomedical applications as drug delivery.

Type
Research Letters
Information
MRS Communications , Volume 8 , Issue 3 , September 2018 , pp. 1335 - 1342
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Copyright
Copyright © Materials Research Society 2018 

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