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From polydisperse diatomaceous earth to biosilica with specific morphologies by glucose gradient/dialysis: a natural material for cell growth

Published online by Cambridge University Press:  02 May 2017

S.R. Cicco ,
D. Vona ,
G. Leone ,
M. Lo Presti ,
F. Palumbo ,
E. Altamura ,
R. Ragni  and
G.M. Farinola
S.R. Cicco
Affiliation:
CNR-ICCOM-Via Orabona, 4- 70125 Bari, Italy
D. Vona
Affiliation:
Università degli Studi di Bari «Aldo Moro», Via Orabona, 4- 70125 Bari, Italy
G. Leone
Affiliation:
Università degli Studi di Bari «Aldo Moro», Via Orabona, 4- 70125 Bari, Italy
M. Lo Presti
Affiliation:
Università degli Studi di Bari «Aldo Moro», Via Orabona, 4- 70125 Bari, Italy
F. Palumbo
Affiliation:
CNR NANOTEC- Via Orabona, 4- 70125 Bari, Italy
E. Altamura
Affiliation:
Università degli Studi di Bari «Aldo Moro», Via Orabona, 4- 70125 Bari, Italy
R. Ragni
Affiliation:
Università degli Studi di Bari «Aldo Moro», Via Orabona, 4- 70125 Bari, Italy
G.M. Farinola*
Affiliation:
Università degli Studi di Bari «Aldo Moro», Via Orabona, 4- 70125 Bari, Italy
*
Address all correspondence to G.M. Farinola at gianlucamaria.farinola@uniba.it
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Abstract

Starting from polydisperse diatomaceous earth (DE), we proposed an efficient separation method for obtaining different morphologies of biosilica from diatoms. DE is a very low-cost source of silica containing all the differently nanostructured elements. By a glucose gradient/dialysis, three types of biosilica morphologies were achieved: rods, valves, and clusters. We fully characterized the diatom fractions and we used them to produce fluorescent biosilica platforms (“tabs”). These supports exhibited good resistance in water, ethanol, and soft scraping. A preliminary biologic application by testing Saos-2 proliferation was also performed to check osteoblasts-like cells biologic attitude for this scaffolds with tunable nanostructure.

Type
Research Letters
Information
MRS Communications , Volume 7 , Issue 2 , June 2017 , pp. 214 - 220
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Copyright
Copyright © Materials Research Society 2017 

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