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Different hydrogel architectures synthesized by gamma radiation based on chitosan and N,N-dimethylacrylamide

Published online by Cambridge University Press:  23 April 2018

D. Tinoco ,
A. Ortega ,
G. Burillo ,
L. Islas  and
L. García-Uriostegui
D. Tinoco
Affiliation:
Instituto de Ciencias Nucleares, Universidad Nacional Autónoma de México, Ciudad Universitaria 04510, CDMXMéxico
A. Ortega
Affiliation:
Instituto de Ciencias Nucleares, Universidad Nacional Autónoma de México, Ciudad Universitaria 04510, CDMXMéxico
G. Burillo*
Affiliation:
Instituto de Ciencias Nucleares, Universidad Nacional Autónoma de México, Ciudad Universitaria 04510, CDMXMéxico
L. Islas
Affiliation:
School of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, UK
L. García-Uriostegui
Affiliation:
CONACyT - Wood, Cellulose and Paper Research Department, University of Guadalajara, Guadalajara 44100, Jalisco, México
*
Address all correspondence to G. Burillo at burillo@nucleares.unam.mx
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Abstract

The present work focuses on the radiation-modification of chitosan (CS) with N,N-dimethylacrylamide (DMAAm) presented as three different architectures: comb-type grafting hydrogels (net-CS)-g-DMAAm, interpenetrating networks of CS and DMAAm (net-CS)-inter-(net-DMAAm), and semi-interpenetrating networks (net-DMAAm)-inter-CS. The syntheses of different polymeric architectures were realized by gamma irradiation by a 60Co source. The optimum conditions for the syntheses of the three systems were at a dose of 6 kGy. Only the comb-type system presented a well-defined critical pH. All the hydrogels showed porous and interconnected structures according to scanning electronic microscopy. These different architectures could be used as three-dimensional cell culture scaffolding.

Type
Research Letters
Information
MRS Communications , Volume 8 , Issue 2 , June 2018 , pp. 617 - 623
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Copyright
Copyright © Materials Research Society 2018 

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