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Novel Developments in High-frequency Micro-Ultrasound Imaging

Published online by Cambridge University Press:  14 March 2018

Tom Little
Tom Little*
Affiliation:
VisualSonks Inc., Toronto, Ontario, Canada

Extract

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With the mapping of the mouse genome, the growing sophistication in transgenic sciences creating complex mouse models of disease, and the demand to study disease in vivo, there has been a corresponding increase in the demand for and development of preclinical imaging modalities. Clinical ultrasound operating in the 2-12 MHz range is a well established clinical imaging modality, accounting for more than one-third of all imaging procedures performed in North America. The simplicity, ease of use, speed, and safety of ultrasound have led to its significant role in diagnosis, treatment assessment, follow-up, and guidance of therapy in clinical applications. Ultrasound imaging is used routinely in its B-Mode imaging mode to report on soft tissue structures. It's also used in its Doppler modes for the measurement of blood velocity in fast-flowing targets such as the cardiovascular system, in slow-flowing applications such as quantifying blood flow and in vascular architectures within tumors.

Type
Research Article
Information
Microscopy Today , Volume 14 , Issue 3 , May 2006 , pp. 18 - 21
Copyright
Copyright © Microscopy Society of America 2006

References

Select References:

Noninvasive Localization of Nuclear Factor of Activated T Cells cl-/- Mouse Embryos by Ultrasound Biomicroscopy-Doppler Allows Genotype-phenotype Correlation. Phoon, CK et al., J Am Soc Echocardiogr. 2005 Dec;18(12):1415-21Google Scholar
Image-Guided Cardiac Cell Delivery Using High-Resolution Small-Animal Ultrasound. Gambhir, S. et al, Molecular Therapy; 2005 Aug 16;Google Scholar
A new three-dimensional ultrasound microimaging technology for preclinical studies using a transgenic prostate cancer mouse model. Lacefield, JC. Et al, Cancer Res. 2005 Jul 15;65(14):6337-45.Google Scholar
Noninvasive measurement of abdominal aortic aneurysms in intact mice by a high-frequency ultrasound imaging system. Wang, YX et al., Ultrasound Med Biol. 2005 Jun; 31(6):745-9.Google Scholar
Abnormal cardiac inflow patterns during postnatal development in a mouse model of Holt-Oram syndrome.f Foster, FS., et al., Am J Physiol Heart Circ Physiol, 2005 Apr 22Google Scholar
Ultrasonic detection and developmental changes in calcification of the placenta during normal pregnancy in mice, Adamson, SL. et al, Placenta, 2005 Feb-Mar; 26(2-3):129-37.Google Scholar