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Structural Studies of an Anti-SARS-CoV-2 Antibody Cocktail

Published online by Cambridge University Press:  30 July 2021

Matthew Franklin ,
Annabel Romero Hernandez ,
Kei Saotome ,
Yi Zhou ,
Alina Baum ,
Christos Kyratsous ,
Lawrence Shapiro ,
Gabriele Cerutti  and
David Ho
Matthew Franklin
Affiliation:
Regeneron Pharmaceuticals, United States
Annabel Romero Hernandez
Affiliation:
Regeneron Pharmaceuticals, United States
Kei Saotome
Affiliation:
Regeneron Pharmaceuticals, United States
Yi Zhou
Affiliation:
Regeneron Pharmaceuticals, United States
Alina Baum
Affiliation:
Regeneron Pharmaceuticals, United States
Christos Kyratsous
Affiliation:
Regeneron Pharmaceuticals, United States
Lawrence Shapiro
Affiliation:
Columbia University, United States
Gabriele Cerutti
Affiliation:
Columbia University, United States
David Ho
Affiliation:
Columbia University, United States

Abstract

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Type
Cryo-EM in Drug Discovery
Information
Microscopy and Microanalysis , Volume 27 , Supplement S1 , August 2021 , pp. 2844 - 2846
Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press on behalf of the Microscopy Society of America

References

Hansen, J, Baum, A, Pascal, KE, Russo, V, Giordano, S, Wloga, E, Fulton, BO, Yan, Y, Koon, K, Patel, K, Chung, KM, Hermann, A, Ullman, E, Cruz, J, Rafique, A, Huang, T, Fairhurst, J, Libertiny, C, Malbec, M, Lee, WY, Welsh, R, Farr, G, Pennington, S, Deshpande, D, Cheng, J, Watty, A, Bouffard, P, Babb, R, Levenkova, N, Chen, C, Zhang, B, Romero Hernandez, A, Saotome, K, Zhou, Y, Franklin, M, Sivapalasingam, S, Lye, DC, Weston, S, Logue, J, Haupt, R, Frieman, M, Chen, G, Olson, W, Murphy, AJ, Stahl, N, Yancopoulos, GD, Kyratsous, CA. Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail. Science. 2020 Aug 21;369(6506):1010-1014. doi: 10.1126/science.abd0827. Epub 2020 Jun 15. PMID: 32540901; PMCID: PMC7299284.CrossRefGoogle ScholarPubMed