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Structural and Chemical Analysis of Hydroxyapatite (HA)-Boron Nitride (BN) Nanocomposites Sintered Under Different Atmospheric Conditions

Published online by Cambridge University Press:  24 August 2017

Feray Bakan ,
Meltem Sezen ,
Merve Gecgin ,
Yapincak Goncu  and
Nuran Ay
Feray Bakan*
Affiliation:
Sabanci University Nanotechnology Research and Application Center (SUNUM), Orhanlı, 34956 Istanbul, Turkey
Meltem Sezen
Affiliation:
Sabanci University Nanotechnology Research and Application Center (SUNUM), Orhanlı, 34956 Istanbul, Turkey
Merve Gecgin
Affiliation:
Department of Materials Science and Engineering, Anadolu University, 26000 Eskisehir, Turkey
Yapincak Goncu
Affiliation:
BORTEK Boron Technologies & Mechatronics Inc., 26110 Eskisehir, Turkey
Nuran Ay
Affiliation:
Department of Materials Science and Engineering, Anadolu University, 26000 Eskisehir, Turkey
*
*Corresponding author. feraybakan@sabanciuniv.edu
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Abstract

Calcium phosphate derivatives have been widely employed in medical and dental applications for hard tissue repair, as they are the main inorganic constitution of hard tissue; such as bones and teeth. Owing to their excellent osteoconductive and bioactive properties, hydroxyapatite- (HA) based ceramics are the best candidates of this group for medical, bioscience, and dental applications. However, when replacing a bone or tooth, HA is not able to sustain similar mechanical properties. In this study, to improve the mechanical properties, nanoscale hexagonal boron nitride with different compositional percentages was added to the nano HA to form composites. The effect of compositional changes and sintering parameters on microstructural and morphological properties of the ceramic composites was comparatively investigated. Detailed chemical characterization of the composite materials was carried out using X-ray diffraction, Fourier transform infrared spectroscopy, Raman spectroscopy, and energy-dispersive X-ray spectroscopy, whereas scanning electron microscopy and atomic force microscopy investigations were employed to monitor morphological and surface features. Additional transmission electron microscopy investigations were carried out to reveal the nanostructure and crystal structure of the composites.

Keywords

hydroxyapatiteboron nitridenanocompositesinteringcharacterization
Type
Materials Science Applications
Information
Microscopy and Microanalysis , Volume 23 , Issue 5 , October 2017 , pp. 891 - 899
Copyright
© Microscopy Society of America 2017 

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References

Bakan, F., Lacin, O. & Sarac, H. (2013). A novel low temperature sol–gel synthesis process for thermally stable nano crystalline hydroxyapatite. Powder Technol 233, 295–302.Google Scholar
Bose, S., Benerjee, S., Dasgupta, A. & Bandyopadhyay, A. (2009). Synthesis, processing, mechanical and biological property characterization of hydroxyapatite whisker-reinforced hydroxyapatite composites. J Am Ceram Soc 92, 323–330.Google Scholar
De Aza, P.N., Guitian, F., Santos, C., De aza, S., Cusco, R. & Artus, L. (1997). Vibrational investigation of calcium phosphate compounds 2. Comparison between hydroxyapatite and β-tricalcium phosphate. Chem Mater 9, 916–922.Google Scholar
Griffith, W.P. (1970). Raman studies on rock-forming minerals. Part II. Minerals containing MO3, MO4, and MO6 groups. J Chem Soc A 1970, 286–291.Google Scholar
Hakki, S.S., Bozkurt, B.S. & Hakki, E.E. (2010). Boron regulates mineralized tissue-associated proteins in osteoblasts (MC3T3-E1). J Trace Elem Med Biol 24, 243–250.Google Scholar
Halici, Z., Polat, B., Karakus, E., Bayir, Y., Albayrak, A., Aydin, A., Cadirci, E. & Ay, N. (2015). Effects of boron nitride and/or hydroxyapatite compounds on bone defect model of rats. In Osteoporosis International With Other Metabolic Bone Diseases, Kanis J.A. & Lindsay R. (Eds.), pp. S338–S339. Milan, Italy: Springer.Google Scholar
Hayakawa, S., Li, Y., Tsuru, K., Osaka, A., Fujii, E. & Kawabata, K. (2009). Preparation of nanometer-scale rod array of hydroxyapatite crystal. Acta Biomater 5, 2152–2160.Google Scholar
Khalil, K.A., Almajid, A.A. & Soliman, M.S. (2011). Effect of hydroxide ion concentration on the morphology of the hydroxyapatite nanorods synthesized using electrophoretic deposition. Mater Sci Appl 2, 105–110.Google Scholar
Kostoglou, N., Polychronopoulou, K. & Rebholz, C. (2015). Thermal and chemical stability of hexagonal boron nitride (h-BN) nanoplatelets. Vacuum 112, 42–45.Google Scholar
Lahiri, D., Singh, V., Benaduce, A.P., Seal, S., Kos, L. & Agarwal, A. (2011). Boron nitride nanotube reinforced hydroxyapatite composite: Mechanical and tribological performance and in-vitro biocompatibility to osteoblasts. J Mech Behav Biomed Mater 4(1), 44–56.Google Scholar
Lian, G., Zhang, X., Zhu, L., Tan, M., Cui, D. & Wang, Q. (2010). A facile solid state reaction route towards nearly monodisperse hexagonal boron nitride nanoparticles. J Mater Chem 20, 3736–3742.Google Scholar
Lipp, A., Schwetz, K.A. & Hunold, K. (1989). Hexagonal boron nitride: Fabrication, properties and applications. J Eur Ceram Soc 5, 3–9.Google Scholar
Lu, X., Zhang, H., Guo, Y., Wang, Y., Ge, X., Leng, Y. & Watari, F. (2011). Hexagonal hydroxyapatite formation on TiO2 nanotubes under urea modulation. CrystEngComm 13, 3741.Google Scholar
Markova, I. (2010). Infrared spectroscopy investigation of metallic nanoparticles based on copper, cobalt and nickel synthesized through borohydride reduction method (review). J Univ Chem Technol Metallurgy 45, 351–378.Google Scholar
Mazaheri, M., Haghighatzadeh, M., Zahedi, A.M. & Sadrnezhaad, S.K. (2009). Effect of a novel sintering process on mechanical properties of hydroxyapatite ceramics. J Alloys Compd 471, 180–184.Google Scholar
Oda, K. (1993). Oxidation kinetics of hexagonal boron nitride powder. J Mater Sci 28, 6562–6566.Google Scholar
Okada, M., Omori, Y., Awata, M., Shirai, T., Matsumoto, N., Takeda, S. & Furuzono, T. (2014). Influence of calcination conditions on dispersibility and phase composition of hydroxyapatite crystals calcined with anti-sintering agents. J Nanopart Res 16, 2469.Google Scholar
O’Shea, D.C., Bartlett, M.L. & Young, R.A. (1974). Compositional analysis of apatites with laser-Raman spectroscopy: (OH, F, Cl) apatites. Arch Oral Biol 19, 995–1006.Google Scholar
Ossi, P.M. & Miotello, A. (2001). Structure and mechanical properties of nanocrystalline boron nitride thin films. Appl Organomet Chem 15, 430–434.Google Scholar
Peak, D., Luther, G.W. & Sparks, D.L. (2003). ATR-FTIR spectroscopic studies of boric acid adsorption on hydrous feric oxide. Geochim Cosmochim Acta 67, 2551–2560.Google Scholar
Sauer, G.R., Zunic, W.B., Durig, J.R. & Wuthier, R.E. (1994). Fourier transform Raman spectroscopy of synthetic and biological calcium phosphates. Calcif Tissue Int 54, 414–420.Google Scholar
Shi, X., Wang, S., Yang, H., Duan, X. & Dong, X (2008). Fabrication and characterization of hexagonal boron nitride powder by spray drying and calcining–nitriding technology. J Solid State Chem 181, 2274–2278.Google Scholar
Siquera, R.L., Yoshida, I.V.P., Pardini, L.C. & Schiavon, M.A. (2007). Poly(borosiloxanes) as precursors for carbon fiber ceramic matrix composites. Mat Res 10(2), 147–151.Google Scholar
Tang, C., Bando, Y., Zhi, C. & Golberg, D. (2007). Boron–oxygen luminescence centres in boron–nitrogen systems. Chem Commun 44, 4599–4601.Google Scholar
Tasli, P.N., Dogan, A., Demirci, S. & Sahin, F. (2013). Boron enhances odontogenic and osteogenic differentiation of human tooth germ stem cells (hTGSCs) in vitro. Biol Trace Elem Res 153(1), 419–427.Google Scholar
Topcu, A., Halici, Z., Karakus, E., Cadici, E. & Dogan, A. (2015). Effects of boron nitride and/or hydroxyapatite compounds on bone defect in osteoporotic rats. In Osteoporosis International With Other Metabolic Bone Diseases, Kanis J.A. & Lindsay R. (Eds.), p. 680. Milan, Italy: Springer.Google Scholar
Tsuda, H. & Arends, J. (1993). Raman spectra of human dental calculus. J Dent Res 72, 1609–1613.CrossRefGoogle ScholarPubMed
Ugarov, M.V., Ageev, V.P & Konov, V.I. (1995). Chemical vapour deposition of boron nitride films stimulated by ultraviolet radiation pulses from a KrF excimer laser. Quant Electron 25(7), 679–683.Google Scholar
Ugarov, M.V., Ageev, V.P. & Karabutov, A.V. (1999). UV laser induced interfacial synthesis of CN-BCN layers on diamond films in borazine and ammonia. Appl Surf Sci 138–139(1–4), 359–363.Google Scholar
Vilcarromero, J., Carreno, M.N.P. & Pereyra, I. (2000). Mechanical properties of boron nitride thin films obtained by RF-PECVD at low temperatures. Thin Solid Films 373, 273–276.Google Scholar
Wang, J. & Shaw, L.L. (2009). Nanocrystalline hydroxyapatite with simultaneous enhancements in hardness and toughness. Biomater 30, 6565–6572.Google Scholar
Wang, L., Hang, R., Xu, Y., Guo, C. & Qian, Y. (2014). From ultrathin nanosheets, triangular plates to nanocrystals with exposed (102) facets, a morphology and phase transformation of sp2 hybrid BN nanomaterials. RSC Adv 4, 14233–14240.Google Scholar
Yayla, M., Halici, Z., Cadirci, E., Karakus, E. & Demirci, S. (2015). Effects of boron nitride and/or hydroxyapatite compounds on bone formation in rat carvarial defect model. In Osteoporosis International With Other Metabolic Bone Diseases, Kanis J.A. & Lindsay R. (Eds.), p. 678. Milan, Italy: Springer.Google Scholar
Ying, X., Cheng, S., Wang, W., Lin, Z., Chen, Q., Zhang, W., Kou, D., Shen, Y., Cheng, X., An Rompis, F., Peng, L. & Zhu Lu, C. (2011). Effect of boron on osteogenic differentiation of human bone marrow stromal cells. Biol Trace Elem Res 44(1), 306–315.CrossRefGoogle Scholar