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Glutamine Addiction: An Achilles Heel for MYC-Overexpressing Breast Cancer

Published online by Cambridge University Press:  04 August 2017

E. Jiang  and
A. Waldron
E. Jiang
Affiliation:
Bergen County Academies, Nano-Structural Imaging Lab, 200 Hackensack Avenue, Hackensack, NJ 07601
A. Waldron
Affiliation:
Bergen County Academies, Nano-Structural Imaging Lab, 200 Hackensack Avenue, Hackensack, NJ 07601

Abstract

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Type
Abstract
Information
Microscopy and Microanalysis , Volume 23 , Supplement S1: Proceedings of Microscopy & Microanalysis 2017 , July 2017 , pp. 1338 - 1339
Copyright
© Microscopy Society of America 2017 

References

[1] Wise, D, et al Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction. PNAS. 2008 Dec 2 105(48), 182–187.CrossRefGoogle Scholar
[2] Gao, J, et al. (2013). Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal. Science Signaling 6(269.CrossRefGoogle ScholarPubMed
[3] Wise, D & Thompson, C Glutamine addiction: a new therapeutic target in cancer. Trends Biochem Sci 2010 Aug35(8), 427–433.CrossRefGoogle ScholarPubMed