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Neurocognitive predictors of financial capacity across the dementia spectrum: Normal aging, mild cognitive impairment, and Alzheimer’s disease

Published online by Cambridge University Press:  01 March 2009

MEGAN G. SHEROD ,
H. RANDALL GRIFFITH ,
JACQUELYNN COPELAND ,
KATHERINE BELUE ,
SARA KRZYWANSKI ,
EDWARD Y. ZAMRINI ,
LINDY E. HARRELL ,
DAVID G. CLARK ,
JOHN C. BROCKINGTON  and
RICHARD E. POWERS
...Show all authors
MEGAN G. SHEROD
Affiliation:
Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama Alzheimer’s Disease Research Center, University of Alabama at Birmingham, Birmingham, Alabama
H. RANDALL GRIFFITH
Affiliation:
Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama Alzheimer’s Disease Research Center, University of Alabama at Birmingham, Birmingham, Alabama
JACQUELYNN COPELAND
Affiliation:
Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama Alzheimer’s Disease Research Center, University of Alabama at Birmingham, Birmingham, Alabama
KATHERINE BELUE
Affiliation:
Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama
SARA KRZYWANSKI
Affiliation:
Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama Alzheimer’s Disease Research Center, University of Alabama at Birmingham, Birmingham, Alabama
EDWARD Y. ZAMRINI
Affiliation:
Department of Neurology, University of Utah, Salt Lake City, Utah
LINDY E. HARRELL
Affiliation:
Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama Alzheimer’s Disease Research Center, University of Alabama at Birmingham, Birmingham, Alabama Veterans Administration Medical Center, Birmingham, Alabama
DAVID G. CLARK
Affiliation:
Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama Alzheimer’s Disease Research Center, University of Alabama at Birmingham, Birmingham, Alabama Veterans Administration Medical Center, Birmingham, Alabama
JOHN C. BROCKINGTON
Affiliation:
Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama Alzheimer’s Disease Research Center, University of Alabama at Birmingham, Birmingham, Alabama
RICHARD E. POWERS
Affiliation:
Alzheimer’s Disease Research Center, University of Alabama at Birmingham, Birmingham, Alabama Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama State of Alabama Department of Mental Health and Mental Retardation, Montgomery, Alabama
DANIEL C. MARSON*
Affiliation:
Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama Alzheimer’s Disease Research Center, University of Alabama at Birmingham, Birmingham, Alabama
*
*Correspondence and reprint requests to: Daniel C. Marson, Department of Neurology, University of Alabama at Birmingham, 650 Sparks Center, 1720 7th Avenue South, Birmingham, Alabama 35294-0017. E-mail: dmarson@uab.edu
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Abstract

Financial capacity is a complex instrumental activity of daily living critical to independent functioning of older adults and sensitive to impairment in patients with amnestic mild cognitive impairment (MCI) and Alzheimer’s disease (AD). However, little is known about the neurocognitive basis of financial impairment in dementia. We developed cognitive models of financial capacity in cognitively healthy older adults (n = 85) and patients with MCI (n = 113) and mild AD (n = 43). All participants were administered the Financial Capacity Instrument (FCI) and a neuropsychological test battery. Univariate correlation and multiple regression procedures were used to develop cognitive models of overall FCI performance across groups. The control model (R2 = .38) comprised (in order of entry) written arithmetic skills, delayed story recall, and simple visuomotor sequencing. The MCI model (R2 = .69) comprised written arithmetic skills, visuomotor sequencing and set alternation, and race. The AD model (R2 = .65) comprised written arithmetic skills, simple visuomotor sequencing, and immediate story recall. Written arithmetic skills (WRAT-3 Arithmetic) was the primary predictor across models, accounting for 27% (control model), 46% (AD model), and 55% (MCI model) of variance. Executive function and verbal memory were secondary model predictors. The results offer insight into the cognitive basis of financial capacity across the dementia spectrum of cognitive aging, MCI, and AD. (JINS, 2009, 15, 258–267.)

Keywords

Financial capacityIADLsCognitive predictorsCognitive agingMCIAD
Type
Research Articles
Information
Journal of the International Neuropsychological Society , Volume 15 , Issue 2 , March 2009 , pp. 258 - 267
Copyright
Copyright © INS 2009

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