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Volumetric modulated arc therapy versus 3D conformal radiotherapy for selected childhood neoplasms

Published online by Cambridge University Press:  21 November 2014

Marzanna Chojnacka ,
Anna Zygmuntowicz-Piętka ,
Anna Semaniak ,
Katarzyna Pędziwiatr ,
Ryszard Dąbrowski  and
Anna Skowrońska-Gardas
Marzanna Chojnacka*
Affiliation:
Department of Radiotherapy, M. Skłodowska-Curie Memorial Cancer Center-Institute, Warsaw, Wawelska, Poland
Anna Zygmuntowicz-Piętka
Affiliation:
Department of Medical Physics, M. Skłodowska-Curie Memorial Cancer Center-Institute, Warsaw, Wawelska, Poland
Anna Semaniak
Affiliation:
Department of Medical Physics, M. Skłodowska-Curie Memorial Cancer Center-Institute, Warsaw, Wawelska, Poland
Katarzyna Pędziwiatr
Affiliation:
Department of Radiotherapy, M. Skłodowska-Curie Memorial Cancer Center-Institute, Warsaw, Wawelska, Poland
Ryszard Dąbrowski
Affiliation:
Department of Medical Physics, M. Skłodowska-Curie Memorial Cancer Center-Institute, Warsaw, Wawelska, Poland
Anna Skowrońska-Gardas
Affiliation:
Department of Radiotherapy, M. Skłodowska-Curie Memorial Cancer Center-Institute, Warsaw, Wawelska, Poland
*
Correspondence to: Marzanna Chojnacka, Department of Radiotherapy, M. Skłodowska-Curie Memorial Cancer Center-Institute, 00-973 Warsaw, Wawelska 15, Poland. Tel/Fax: +48225709186. E-mail: marzanna.ch1@wp.pl
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Abstract

Aim

The comparative study of the plan quality between volumetric modulated arc therapy (VMAT) and 3D conformal therapy (3DCRT) for the treatment of selected representative childhood neoplasms was performed.

Materials and methods

During the year 2013, 44 children with neoplasms were irradiated using VMAT. The 3DCRT plans were created retrospectively and compared with the VMAT plans for four tumour locations. The conformity parameters, dose volume histograms for target volume and organs at risk, number of monitor units and time used to deliver the single fraction were evaluated and compared for each plan. Additionally, for patients with brain tumour the comparison of different arcs configuration was made.

Results

VMAT modality presented the superiority over older conformal methods with regard to the improvement in the dose conformity and normal tissue sparing. The noncoplanar arcs arrangement was beneficial in the decrease of high-dose volume and the protection of the organs at risk located oppositely to the target volume.

Findings

VMAT could be preferred technique for treating childhood neoplasms, especially when the complex-shaped target volume is localised close to the critical structures. The noncoplanar arcs arrangement could be the method of choice in the reirradiated patients and in these with laterally located brain tumours.

Keywords

VMATconformal radiotherapychildhood neoplasms
Type
Original Articles
Information
Journal of Radiotherapy in Practice , Volume 14 , Issue 1 , March 2015 , pp. 35 - 42
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Copyright
© Cambridge University Press 2014 

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