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The much-awaited Venezia applicator: virtues of combined intracavitary and interstitial brachytherapy in locally advanced cervical cancer

Published online by Cambridge University Press:  28 August 2018

Aparna Gangopadhyay*
Affiliation:
Department of Radiotherapy, Medical College Hospitals, Kolkata, India
Subrata Saha
Affiliation:
Department of Radiotherapy, Medical College Hospitals, Kolkata, India
*
Author for correspondence: Aparna Gangopadhyay, Department of Radiotherapy, Medical College Hospitals, 88 College Street, Kolkata 700073, India. Tel: +913325410088. E-mail: mails7778@gmail.com

Summary

Locally advanced cervix cancer is a major health problem in resource-limited areas of the world. Brachytherapy following pelvic chemoradiation is challenging, as large irregular clinical target volumes need adequate dose delivery while respecting limits of normal tissue tolerance. Achieving this is practically impossible using intracavitary brachytherapy alone. Consequently, combined intracavitary and interstitial brachytherapy provides higher chances of local control.

Type
Short Communication
Copyright
© Cambridge University Press 2018 

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References

1. Walter, F, Maihöfer, C, Schüttrumpf, L et al. Combined intracavitary and interstitial brachytherapy of cervical cancer using the novel hybrid applicator Venezia: Clinical feasibility and initial results. Brachytherapy 2018; pii: S1538-4721(18)30112-0. doi: 10.1016/j.brachy.2018.05.009. [Epub ahead of print] PubMed PMID: 29941345.Google Scholar
2. Ferlay, J., Soerjomataram, I, Ervik, M et al. Cancer incidence and mortality worldwide: IARC Cancer Base No. 11. Lyon, France: International Agency for Research on Cancer, 2013.Google Scholar
3. Bruni, L, Barrionuevo-Rosas, L, Albero, G et al. ICO/IARC Information Centre on HPV and Cancer (HPV Information Centre). Institut Català d’Oncologia, Barcelona, Spain. Human Papillomavirus and Related Diseases in India. Summary Report 27 July 2017. [27 July 2018].Google Scholar
4. Pötter, R, Haie-Meder, C, Van Limbergen, E et al. GEC ESTRO Working Group. Recommendations from gynaecological (GYN) GEC ESTRO working group (II): concepts and terms in 3D image-based treatment planning in cervix cancer brachytherapy-3D dose volume parameters and aspects of 3D image-based anatomy, radiation physics, radiobiology. Radiother Oncol 2006; 78 (1): 6777. [Epub 2006 Jan 5] PubMed PMID: 16403584.Google Scholar
5. Handa, VL, Lockhart, ME, Fielding, JR et al. Pelvic floor disorders network. Racial differences in pelvic anatomy by magnetic resonance imaging. Obstet Gynecol 2008; 111 (4): 914920. https://doi.org/10.1097/AOG.0b013e318169ce03 PubMed PMID: 18378751; PubMed Central PMCID: PMC2593128.Google Scholar
6. Sen, NC. A study of Bengalee and Beharee female pelvis by roentgen-pelvimetric method. Ind Med Gaz 1949; 84 (8): 337342. PubMed PMID: 15408312; PubMed Central PMCID: PMC5189474.Google Scholar