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Dosimetric comparison of three-dimensional (3D), intensity-modulated radiotherapy (IMRT) and hybrid IMRT for left-sided postmastectomy radiation therapy (PMRT)

Published online by Cambridge University Press:  29 June 2023

Siwika Thongthanom  and
Wannapha Nobnop Open the ORCID record for Wannapha Nobnop [Opens in a new window]
Siwika Thongthanom
Affiliation:
Graduate School, Medical Physics Program, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand Department of Radiology, Samutsakhon Hospital, Samutsakhon, Thailand
Wannapha Nobnop*
Affiliation:
The Division of Radiation Oncology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand Northern Thai Research Group of Radiation Oncology (NTRG-RO), Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
*
Corresponding author: Wannapha Nobnop; Email: wannapha.n@cmu.acth
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Abstract

Purpose:

This study aimed to determine the suitable breast treatment technique for a small facility’s hospital with limited staff and equipment resources. The benefits and drawbacks of each technique should be considered to guide radiation oncologists choose the appropriate treatment option for postmastectomy radiation therapy (PMRT) patients.

Methods and Materials:

This study included the computed tomography images of 15 patients who received left-sided PMRT. The patient’s characteristics were classified into two groups: 1. irradiation of only the chest wall (CW) and 2. CW lymph nodes plus supraclavicular lymph nodes (SPCs). All 15 PMRT patients were generated in 4 treatment techniques including 3DCRT, field-in-field (FiF), intensity-modulated radiotherapy (IMRT) and hybrid (3DCRT + IMRT). Each treatment technique’s dosimetric parameters and treatment time were compared.

Result:

All four treatment plans met the acceptable criteria. The IMRT plans achieved the highest plan quality scores for two groups of PMRT patients but require the longest treatment time, whereas the 3DCRT and FiF plans demonstrated superiority for organ at risk (OAR) sparing and required the shortest treatment time when compared with the IMRT and hybrid plans.

Conclusion:

The IMRT plan had the highest plan quality but required the most time to treat. Treatment times are critical in facilities with limited resources. As a result, the FiF plan was found to be a suitable technique for both CW-only and CW plus SPC irradiation due to its short treatment time and high plan quality scores for OAR dose sparing.

Keywords

dosimetrichybrid IMRTIMRTpostmastectomytreatment time
Type
Original Article
Information
Journal of Radiotherapy in Practice , Volume 22 , 2023 , e105
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Copyright
© The Author(s), 2023. Published by Cambridge University Press

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