Hostname: page-component-848d4c4894-nmvwc Total loading time: 0 Render date: 2024-06-25T16:40:17.216Z Has data issue: false hasContentIssue false
  • English
  • Français

Contemplation of head and neck intensity-modulated radiotherapy

Published online by Cambridge University Press:  01 June 2008

T.A. Rose
T.A. Rose
Affiliation:
Cancer Centre of the Southern Interior, Kelowna, British Columbia, Canada
Get access Rights & Permissions [Opens in a new window]

Abstract

Intensity-modulated radiootherapy (IMRT) is being rapidly embraced as a radiotherapy technique in many cancer centres across the world. This paper aims to highlight the reported problems associated with the use of IMRT for the treatment of head and neck cancer. Specific areas of concern that are mentioned are the identification of tumour volumes, reproducibility of treatment, issues of tumour resistance and tumour recurrence. Radiotherapy departments are advised to make haste slowly when considering the implementation of this technique.

Keywords

Head and neck irradiationintensity-modulated radiotherapyreproducibility
Type
Original Article
Information
Journal of Radiotherapy in Practice , Volume 7 , Issue 2 , June 2008 , pp. 61 - 66
Copyright
Copyright © Cambridge University Press 2008

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Galvin, JM.Alternative methods for intensity-modulated radiation therapy inverse planning and dose delivery. Semin Radiat Oncol 2006;16 (4):218–223.CrossRefGoogle ScholarPubMed
Feng, M, Eisbruch, A.Future issues in highly conformal radiotherapy for head and neck cancer. J Clin Oncol 2007;1025 (8):1009–1013.CrossRefGoogle Scholar
Gregoire, V, Levendag, P, Ang, KK, et al. CT-based delineation of lymph node levels and related CTVs in the node-negative neck: DAHANCA, EORTC, GORTEC, NCIC,RTOG consensus guidelines. Radiother Oncol 2003;69 (3):227–236.CrossRefGoogle ScholarPubMed
Gregoire, V, Eisbruch, A, Hamoir, M, Levendag, P.Proposal for the delineation of the nodal CTV in the node-positive and the post-operative neck. Radiother Oncol 2006; 79(1):15–20.CrossRefGoogle ScholarPubMed
Eisbruch, A, Marsh, LH, Dawson, LA, et al. Recurrences near base of skull after IMRT for head-and-neck cancer: implications for target delineation in high neck and for parotid gland sparing. Int J Radiat Oncol Biol Phys 2004; 159 (1):28–42CrossRefGoogle Scholar
Bussels, B, Maes, A, Hermans, R, Nuyts, S, Weltens, C, Van den Bogaert, W.Recurrences after conformal parotid-sparing radiotherapy for head and neck cancer. Radiother Oncol 2004; 72 (2):119–127.CrossRefGoogle ScholarPubMed
ICRU report 62: Prescribing, recording, and reporting photon beam therapy (supplement to ICRU report 50). Bethesda, MD; 1999.Google Scholar
Suzuki, M, Nishimura, Y, Nakamatsu, K, Okumura, M, Hashiba, H, Koike, R, Kanamori, S, Shibata, T.Analysis of interfractional set-up errors and intrafractional organ motions during IMRT for head and neck tumors to define an appropriate planning target volume (PTV)- and planning organs at risk volume (PRV)-margins. Radiother Oncol 2006; 78 (3):283–290.CrossRefGoogle ScholarPubMed
Hong, TS, Tome, WA, Chappell, RJ, Chinnaiyan, P, Mehta, MP, Harari, PM.The impact of daily setup variations on head-and-neck intensity-modulated radiation therapy. Int J Radiat Oncol Biol Phys 2005; 161 (3):779–788.CrossRefGoogle Scholar
Prisciandaro, JI, Frechette, CM, Herman, MG, Brown, PD, Garces, YI, Foote, RL.A methodology to determine margins by EPID measurements of patient setup variation and motion as applied to immobilization devices. Med Phys 2004; 31 (11):2978–2988.CrossRefGoogle ScholarPubMed
Mohan, R, Zhang, X, Wang, H, Kang, Y, Wang, X, Liu, H, Ang, KK, Kuban, D, Dong, L.Use of deformed intensity distributions for on-line modification of image-guided IMRT to account for interfractional anatomic changes. Int J Radiat Oncol Biol Phys 2005; 1561 (4):1258–1266.CrossRefGoogle Scholar
Hansen, EK, Bucci, MK, Quivey, JM, Weinberg, V, Xia, P.Repeat CT imaging and replanning during the course of IMRT for head-and-neck cancer. Int J Radiat Oncol Biol Phys 2006; 164 (2):355–362.CrossRefGoogle Scholar
Keall, P.4-dimensional computed tomography imaging and treatment planning. Semin Radiat Oncol 2004; 14 (1):81–90.CrossRefGoogle ScholarPubMed
Unkelbach, J, Oelfke, U.Inclusion of organ movements in IMRT treatment planning via inverse planning based on probability distributions. Phys Med Biol 2004; 749(17):4005–4029.CrossRefGoogle Scholar
Dawson, LA, Anzai, Y, Marsh, L, Martel, MK, Paulino, A, Ship, JA, Eisbruch, A.Patterns of local-regional recurrence following parotid-sparing conformal and segmental intensity-modulated radiotherapy for head and neck cancer. Int J Radiat Oncol Biol Phys 2000; 1546 (5):1117–1126.CrossRefGoogle Scholar
Manning, MA, Wu, Q, Cardinale, RM, Mohan, R, Lauve, AD, Kavanagh, BD, Morris, MM, Schmidt-Ullrich, RK.The effect of setup uncertainty on normal tissue sparing with IMRT for head-and-neck cancer. Int J Radiat Oncol Biol Phys 2001; 151 (5):1400–1409.CrossRefGoogle Scholar
Chao, KS, Ozyigit, G, Tran, BN, Cengiz, M, Dempsey, JF, Low, DA.Patterns of failure in patients receiving definitive and postoperative IMRT for head-and-neck cancer. Int J Radiat Oncol Biol Phys 2003; 155 (2):312–321.CrossRefGoogle Scholar
Lee, N, Xia, P, Fischbein, NJ, Akazawa, P, Akazawa, C, Quivey, JM.Intensity-modulated radiation therapy for head-and-neck cancer: the UCSF experience focusing on target volume delineation. Int J Radiat Oncol Biol Phys 2003; 157 (1):49–60.CrossRefGoogle Scholar
Rades, D, Fehlauer, F, Wroblesky, J, Albers, D, Schild, SE, Schmidt, R.Prognostic factors in head-and-neck cancer patients treated with surgery followed by intensity-modulated radiotherapy (IMRT), 3D-conformal radiotherapy, or conventional radiotherapy. Oral Oncol 2007; 43 (6):535–543.CrossRefGoogle ScholarPubMed
Studer, G, Furrer, K, Davis, BJ, Stoeckli, SS, Zwahlen, RA, Luetolf, UM, Glanzmann, C.Postoperative IMRT in head and neck cancer. Radiat Oncol 2006; 1:40.CrossRefGoogle ScholarPubMed
Chambers, MS, Garden, AS, Rosenthal, D, Ahamad, A, Schwartz, DL, Blanco, AI, Chao, KS, Morrison, WH, Ang, KK, Weber, RS.Intensity-modulated radiotherapy: is xerostomia still prevalent? Curr Oncol Rep 2005; 7 (2):131–136.CrossRefGoogle ScholarPubMed
Chao, KS.Protection of salivary function by intensity-modulated radiation therapy in patients with head and neck cancer. Semin Radiat Oncol 2002; 12 (1 Suppl 1):20–25.CrossRefGoogle ScholarPubMed
Eisbruch, A, Ship, JA, Dawson, LA, et al. Salivary gland sparing and improved target irradiation by conformal and intensity modulated irradiation of head and neck cancer. World J Surg 2003; 27 (7):832–837.CrossRefGoogle ScholarPubMed
Yao, M, Chang, K, Funk, GF, Lu, H, Tan, H, Wacha, J, Dornfeld, KJ, Buatti, JM.The failure patterns of oral cavity squamous cell carcinoma after intensity-modulated radiotherapy-the university of Iowa experience. Int J Radiat Oncol Biol Phys 2007; 167 (5):1332–1341.CrossRefGoogle Scholar
Daly, ME, Lieskovsky, Y, Pawlicki, T, et al. Evaluation of patterns of failure and subjective salivary function in patients treated with intensity modulated radiotherapy for head and neck squamous cell carcinoma. Head Neck 2007; 29 (3):211–220.CrossRefGoogle ScholarPubMed