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Comparing treatment plans for stomach cancer: three-dimensional conformal radiotherapy (3D-CRT), physical wedge-based conformal RT (WB-CRT) and intensity-modulated radiotherapy (IMRT)

Published online by Cambridge University Press:  18 January 2021

Gokcen Inan Open the ORCID record for Gokcen Inan [Opens in a new window]  and
Osman Vefa Gul Open the ORCID record for Osman Vefa Gul [Opens in a new window]
Gokcen Inan*
Affiliation:
Faculty of Medicine, Department of Radiation Oncology, Selcuk University, Konya, Turkey
Osman Vefa Gul
Affiliation:
Faculty of Medicine, Department of Radiation Oncology, Selcuk University, Konya, Turkey
*
Author for correspondence: Gokcen Inan, Faculty of Medicine, Department of Radiation Oncology, Selcuk University, Konya, Turkey. E-mail: gokceninan85@gmail.com
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Abstract

Objective:

The aim of this study was to find the optimal radiotherapy (RT) method using three-dimensional (3D) conformal RT (CRT), physical wedge-based CRT (WB-CRT) and dynamic intensity-modulated RT (D-IMRT) techniques for stomach cancer.

Methods:

Ten patients with gastric cancer were selected for this study. For each patient, three different treatment plans were generated. 3D-CRT, WB-CRT and IMRT plans were evaluated in terms of dosimetry. Treatment plans were compared with respect to the planning target volume and organs at risk (OARs) volumes including right and left kidney doses (V13, V20 and V28), heart mean and maximum doses, spinal cord maximum doses, dose homogeneity index, conformity index (CI), delivery time and the monitor unit counts for the treatment. Statistical analysis was performed using the SPSS (Statistical Package for the Social Sciences) v25.1 software (IBM Inc., Chicago, IL, USA).

Results:

In stomach plans, IMRT showed a significantly lower dose for the left and right kidneys than that of WB-CRT or 3D-CRT (p < 0·05). Compared with WB-CRT or 3D-CRT, IMRT reduced the V28, V20, V13 and mean dose to bilateral kidneys (p < 0·05). IMRT plans indicated better dosimetry for at the Dmean of the liver and heart. Concerning the calculated CI, values for IMRT plans gave significant results than other plans (p < 0·05).

Conclusions:

IMRT plans provided better protection for the kidneys, liver, heart and spinal cord. For the treatment of stomach cancer, considering the dose to the OARs, IMRT appears to be the most superior technique.

Keywords

conformal radiotherapyintensity-modulated radiotherapyphysical wedge-based conformal radiotherapy
Type
Original Article
Information
Journal of Radiotherapy in Practice , Volume 21 , Issue 3 , September 2022 , pp. 303 - 308
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Copyright
© The Author(s), 2021. Published by Cambridge University Press

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