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Biomimetic apatite formation on poly(lactic acid) composites containing calcium carbonates

Published online by Cambridge University Press:  31 January 2011

Hirotaka Maeda
Affiliation:
Department of Materials Science and Engineering, Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya 466–8555, Japan
Toshihiro Kasuga*
Affiliation:
Department of Materials Science and Engineering, Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya 466–8555, Japan
Masayuki Nogami
Affiliation:
Department of Materials Science and Engineering, Nagoya Institute of Technology, Gokiso-cho, Showa-ku, Nagoya 466–8555, Japan
Yoshitaka Hibino
Affiliation:
Department of Tissue Engineering, Nagoya University School of Medicine, Turumai-cho, Showa-ku, Nagoya 466–8550, Japan
Ken-Ichiro Hata
Affiliation:
Department of Tissue Engineering, Nagoya University School of Medicine, Turumai-cho, Showa-ku, Nagoya 466–8550, Japan
Minoru Ueda
Affiliation:
Department of Oral and Maxillofacial Surgery, Nagoya University Graduate School of Medicine, Turumai-cho, Showa-ku, Nagoya 466–8550, Japan
Yoshio Ota
Affiliation:
Yabashi Industries Co. Ltd., Akasaka-cho, Ogaki 503–2213, Japan
*
a)Address all correspondence to this author.kasugato@mse.nitech.ac.jp
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Abstract

Poly(lactic acid) composites containing a mixture of calcium carbonates (vaterite, aragonite, and calcite) were prepared by a carbonation process in methanol. Soaking of the composites for 3 h in simulated body fluid (SBF) at 37 °C resulted in the deposition of bonelike apatite particles on the composite surface. After soaking the composites, vaterite phase in the composites was forward to dissolve rapidly, resulting in increase the supersaturation of the apatite in SBF. 13C cross-polarization magic angle spinning nuclear magnetic resonance (13C CP/MAS-NMR) spectra of the composites suggested the formation of a bond between Ca2+ ion and the COO- group, which induces the apatite nucleation. These results may elucidate the mechanism of means to reduce the induction period for apatite formation.

Type
Rapid Communications
Copyright
Copyright © Materials Research Society 2002

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References

1Hench, L.L., J. Am. Ceram. Soc. 74, 1487 (1991).CrossRefGoogle Scholar
2Jarcho, M., Kay, J.F., Gumaer, I., Drobeck, H.P., and Dremus, R.H., J. Bioeng. 1, 79 (1976).Google Scholar
3Kokubo, T., Acta. Materl, 46, 2519 (1998).Google Scholar
4Neo, M., Nakamura, T., Ohtsuki, C., Kokubo, T., and Yamamuro, T., J. Biomed. Mater. Res. 27, 999 (1993).Google Scholar
5Kokubo, T., J. Non-Cryst. Solids 120, 138 (1990).CrossRefGoogle Scholar
6 M. Tanahashi and Matsuda, T., J. Biomed. Mater. Res. 34, 305 (1997).Google Scholar
7Ohtsuki, C., Kokubo, T., and Yamauro, T., J. Non-Cryst. Solids 143, 84 (1992).CrossRefGoogle Scholar
8Kim, H.M., Kishimoto, K., Miyaji, F., Kokubo, T., Yao, T., Suetsugu, Y., and Tanaka, J., J. Mater. Sci. Mater. Med. 11, 421 (2000).Google Scholar
9Yasue, T., Koijma, Y., and Arai, Y., Gypsum Lime (Sekko-toSekkai) 247, 471 (1993) (in Japanese).Google Scholar
10Nakamae, K., Nishiyama, S., Yamashiro, J., Fujimura, Y., Urano, A., Tosaki, Y., and Matsumoto, T., Nippon-Setchaku-Kyoukai-shi 21, 414 (1985) (in Japanese).Google Scholar
11Kokubo, T., Kushitani, H., Ebisawa, Y., Kitsugi, T., Kotani, S., Oura, K., and Yamamuro, T., Proceedings of the 1st International Symposium on Ceramics in Medicine, edited by Oonishi, H., Aoki, H., and Sawai, K. (Ishiyaku EuroAmerica, Tokyo, Japan, 1989), pp. 157162.Google Scholar
12Asada, M., Asada, N., Toyoda, A., Ando, I., and Kurosu, H., J. Mol. Struct. 244, 237 (1991).Google Scholar
13Takadama, H., Kim, H-M., Miyaji, F., Kokubo, T., and Nakamura, T., Proceedings of the 12th International Symposium on Ceramics in Medicine, edited by Ohgushi, H., Hastings, G.W., and Yoshikawa, T. (World Scientific, Singapore, 1999), pp. 109112.Google Scholar