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Oncological and functional outcomes after repeat transoral laser microsurgery for the treatment of recurrent early glottic cancer

Published online by Cambridge University Press:  21 February 2020

D Forner ,
M H Rigby ,
M Corsten ,
J R Trites ,
J Pyne  and
S M Taylor
D Forner*
Affiliation:
Division of Otolaryngology – Head and Neck Surgery, Department of Surgery, Dalhousie University, Halifax, Canada
M H Rigby
Affiliation:
Division of Otolaryngology – Head and Neck Surgery, Department of Surgery, Dalhousie University, Halifax, Canada
M Corsten
Affiliation:
Division of Otolaryngology – Head and Neck Surgery, Department of Surgery, Dalhousie University, Halifax, Canada
J R Trites
Affiliation:
Division of Otolaryngology – Head and Neck Surgery, Department of Surgery, Dalhousie University, Halifax, Canada
J Pyne
Affiliation:
Division of Otolaryngology – Head and Neck Surgery, Department of Surgery, University of Alberta, Edmonton, Canada
S M Taylor
Affiliation:
Division of Otolaryngology – Head and Neck Surgery, Department of Surgery, Dalhousie University, Halifax, Canada
*
Author for correspondence: Dr David Forner, Division of Otolaryngology – Head and Neck Surgery, 5820 University Ave, 3rd Floor Dickson Bldg, Halifax, Nova ScotiaB3H 2Y9, Canada E-mail: david.forner@dal.ca Fax: +1 (902) 473 4384
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Abstract

Background

Transoral laser microsurgery for glottic squamous cell carcinoma is the standard of care at many institutions. Repeat transoral laser microsurgery for recurrence may avoid the need for radiotherapy and total laryngectomy. This study aimed to identify oncological and functional outcomes in a cohort of patients who had undergone repeat transoral laser microsurgery procedures.

Method

A retrospective review of prospectively collected data of patients treated with transoral laser microsurgery for carcinoma in situ or tumour stages T1 or T2 glottic cancer, from 2003 to 2018.

Results

Twenty patients were identified. Additional treatment was not needed in 45 per cent of patients. The five-year overall survival rate was 90 per cent. The disease-specific survival rate was 100 per cent. The laryngeal preservation rate was 85 per cent. There was improvement in mean Voice Handicap Index-10 scores following repeat transoral laser microsurgery treatment, when comparing the pre- and post-operative periods (mean scores = 15.5 vs 11.5, p = 0.373).

Conclusion

Repeat transoral laser microsurgery can be an oncologically safe alternative to other salvage therapies for glottic squamous cell carcinoma recurrence, without sacrificing functional outcomes.

Keywords

Laryngeal NeoplasmsMicrosurgeryVoice QualityLasersGas
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 134 , Issue 2 , February 2020 , pp. 169 - 173
Copyright
Copyright © JLO (1984) Limited, 2020

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Footnotes

Dr D Forner takes responsibility for the integrity of the content of the paper

Presented at the 73rd Canadian Society of Otolaryngology – Head and Neck Surgery Annual Meeting, 1–4 June 2019, Edmonton, Canada.

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