Hostname: page-component-8448b6f56d-dnltx Total loading time: 0 Render date: 2024-04-25T01:06:14.726Z Has data issue: false hasContentIssue false

Nasopharyngeal Corynebacterium ulcerans: a different diptheria

Published online by Cambridge University Press:  29 June 2007

J. P. de Carpentier*
Affiliation:
ENT DepartmentsWythenshawe Hospital
P. M. Flanagan
Affiliation:
ENT DepartmentsWythenshawe Hospital
I. P. Singh
Affiliation:
ENT DepartmentsWythenshawe Hospital
M. S. Timms
Affiliation:
ENT DepartmentsBlackburn Royal Infirmary.
W. Y. Nassar
Affiliation:
ENT DepartmentsWythenshawe Hospital
*
c/o ENT Department, Wythenshawe Hospital, Southmoor Road, Wythenshawe, Manchester M23 9LT.

Abstract

A case of toxigenic Corynebacterium ulcerans infection is presented. The diagnosis was delayed and no anti-toxin administered. A nasopharyngeal biopsy was complicated by severe haemorrhage necessitating a post nasal pack. A brief review of the pathology and treatment of Corynebacterium ulcerans is given.

Type
Clinical Records
Copyright
Copyright © JLO (1984) Limited 1992

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Anon (1987) Communicable Disease Surveillance Centre. Information record (Ref. DIPH II) Diphtheria; annual corrected notifications and deaths in England and Wales from 1914. Communicable Disease Surveillance Centre, 61 Collindale Ave., London NW9 5EQ.Google Scholar
Barrett, N. J. (1986) Communicable disease association with milk and dairy products in England and Wales: 1983–1984. Journal of Infection, 12: 265272.CrossRefGoogle ScholarPubMed
Bostock, A. D., Gilbert, F. R., Lewis, D., Smith, D. C. M. (1984) Corynebacterium ulcerans infection associated with untreated milk. Journal of Infection, 9: 286288.CrossRefGoogle ScholarPubMed
Brooks, R., Joynson, D. H. M. (1990) Bacteriological diagnosis of diphtheria. Association of Clinical Pathologists Broadsheet No. 125. Journal of Clinical Pathology, 43: 576580.CrossRefGoogle Scholar
Carne, H. R., Onon, E. O. (1982) The exotoxins of Corynebacterium ulcerans. Journal of Hygiene (London), 88: 173191.CrossRefGoogle ScholarPubMed
Davis, J. R. (1974) Elek's test for toxigenicity of corynebacterium. In Laboratory methods I., [Willis, A. T. and Collins, C. H., eds.] Public Health Lab. Service Monograph Series No. 5. London Public Health Laboratory Service 17.Google Scholar
Gilbert, R., Stewart, F. C. (1927) Corynebacterium ulcerans; a pathogenic micro-organism resembling Corynebacterium diphtheria. Journal of Laboratory and Clinical Medicine, 12: 756761.Google Scholar
Groman, N., Schiller, J., Russell, J. (1984) Corynebacterium ulcerans and Corynebacterium pseudotuberculosis responses to DNA probes derived from corynecophage B and C. Diphtheria. Infection and Immunity, 45: 511517.CrossRefGoogle Scholar
Harnisch, J. P. (1980) Diphtheria. In Harrison's Principles of Internal Medicine, [Isselbritor, A. B., Adams, R. D., Braunwald, E., Petonsdorf, R. G. and Wilson, J. D., eds.] 9th Edition, McGraw Hill Book Company, New York, p. 671675.Google Scholar
Hart, R. J. C. (1984) Corynebacterium ulcerans in humans and cattle in North Devon. Journal of Hygiene (London), 92: 161164.CrossRefGoogle ScholarPubMed
Leek, M. D., Sivaloganathan, S., Devaray, S. K., Zamiri, I., Groffiths, G. D., Green, M. A. (1990) Diphtheria with a difference—a rare Corynebacterium fatality with associated apototic cell death. Histopathology, 16: 187205.CrossRefGoogle Scholar
McCloskey, R. V. (1985) Corynebacterium diphtheria. In Principles and Practice of Infectious Diseases. [Mandell, G. L., Douglas, R. G., and Bennett, J. E., eds.]. 2nd edition. New York: John Wiley, p. 11711174.Google Scholar
Meers, P. D. (1979) A case of classical diphtheria and other infections due to Corynebacterium Ulcerans. Journal of Infection, 1: 139142.Google Scholar
Pers, C. (1987) Infection due to Corynebacterium ulcerans producing diphtheria toxin. Ada Pathologica Microbiologica et Immunologica Scandanavica Section B (Microbiologica), 95: 361362.Google ScholarPubMed
Petrie, G. R.McLean, D. (1934) The inter-relations of Corynebacterium ovis, Corynebacterium diphtheria, and certain diphtheria strains derived from the human nasopharynx. Journal of Pathology and Bacteriology, 39: 635.CrossRefGoogle Scholar
Stamm, W. E. (1985) Other Corynebacteria. In Principles and Practice of Infectious Diseases, [Mandell, G. L., Douglas, R. G. and Bennett, J. E., eds.] 2nd edition. New York: John Wiley, p. 11741177.Google Scholar