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Multiple symmetrical lipomatosis: case report and literature review

Published online by Cambridge University Press:  15 May 2012

K J Sia ,
I P Tang  and
T Y Tan
K J Sia*
Affiliation:
Department of Otorhinolaryngology, Faculty of Medicine, University of Malaya, Malaysia
I P Tang
Affiliation:
Department of Otorhinolaryngology, Faculty of Medicine, University of Malaya, Malaysia
T Y Tan
Affiliation:
Otorhinolaryngology Department, Sarawak General Hospital, Malaysia
*
Address for correspondence: Dr Kian Joo Sia, 14A, Lorong 4A, Jalan Pipit, 96000 Sibu, Sarawak, Malaysia Fax: 6 082419495 E-mail: kj_sia@yahoo.com
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Abstract

Objective:

To discuss the pathophysiology and various treatment methods of multiple symmetrical lipomatosis.

Case report:

We report a case of multiple symmetrical lipomatosis in a middle-aged man. He presented to us with an extensive, disfiguring neck mass. Clinical examination and computed tomography suggested a lipomatous mass without compression of vital neck structures. The proximity of the lipomatous mass to the carotid sheaths attracted our interest. We performed surgical excision in this case, because of the deep infiltrative behaviour of the lipoma. The benefits and drawbacks of liposuction and surgical excision of extensive neck lipomatosis are discussed.

Conclusion:

Surgical excision and liposuction are complementary treatments in the management of multiple symmetrical lipomatosis. Patients should be aware of the limitations of both surgical options, and the risk of lipoma recurrence, before surgery. The decision on the mode of surgery relies upon the disease extent, the patient's expectations and the surgeon's experience.

Keywords

Multiple Symmetrical LipomatosisMadelung DiseaseLipomaSurgical Procedure, Operative
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 126 , Issue 7 , July 2012 , pp. 756 - 758
Copyright
Copyright © JLO (1984) Limited 2012

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References

1Klopstock, T, Naumann, M, Seibel, P, Shalke, B, Reiners, K, Reichmann, H. Mitochondrial DNA mutations in multiple symmetric lipomatosis. Mol Cell Biochem 1997;174:271–5CrossRefGoogle ScholarPubMed
2Silvestri, G, Ciafaloni, E, Santorelli, FM, Shanske, S, Servidei, S, Graf, WD et al. Clinical features associated with the A-G transition at nucleotide 8344 of mtDNA (‘MERRF mutation’). Neurology 1993;43:1200–6CrossRefGoogle ScholarPubMed
3Ujpál, M, Németh, ZS, Reichwein, A, Szabó, GY. Long-term results following surgical treatment of benign symmetric lipomatosis (BSL). Int J Oral Maxillofac Surg 2001;30:479–83CrossRefGoogle ScholarPubMed
4Chan, ESY, Ahuja, AT, King, AD, Lau, WY. Head and neck cancers associated with Madelung's disease. Ann Surg Oncol 1999;6:395–7CrossRefGoogle ScholarPubMed
5Ruzicka, T, Vieluf, D, Landthaler, M, Braun-Falco, O. Benign symmetric lipomatosis. J Am Acad Dermatol 1987;17:663–74CrossRefGoogle ScholarPubMed
6Guastella, C, Borsi, C, Gibelli, S, Berta, LG. Madelung's lipomatosis associated with head and neck malignant neoplasia: a study of 2 cases. Otolaryngol Head Neck Surg 2002;126:191–2CrossRefGoogle Scholar
7Tizian, C, Berger, A, Vykoupil, K. Malignant degeneration in Madelung's disease. Br J Plast Surg 1983;36:187–9CrossRefGoogle ScholarPubMed
8Durand, JP, Thomine, JM, Tayot, J, Foucault, J, Deshayes, P. Liposarcoma in a Launois-Bensaude disease. French 1973;40:287–91Google Scholar
9Alameda, YA, Torres, L, Perez-Mitchell, C, Riera, A. Madelung disease: a clinical diagnosis. Otol Head Neck Surg 2009;141:418–19CrossRefGoogle ScholarPubMed
10Hasegawa, T, Matsukura, T, Ikeda, S. Mesotherapy for benign symmetric lipomatosis. Aesth Plast Surg 2010;34:153–6CrossRefGoogle ScholarPubMed
11Faga, A, Valdatta, LA, Thione, A, Buoro, M. Ultrasound assisted liposuction for the palliative treatment of Madelung's disease: a case report. Aesthetic Plast Surg 2001;25:181–3CrossRefGoogle ScholarPubMed
12Verhelle, NA, Nizet, JL, Van den Hof, B, Guelinckx, P, Heymans, O. Liposuction in benign symmetric lipomatosis: sense or senseless. Aesthetic Plast Surg 2003;27:319–21CrossRefGoogle ScholarPubMed
13Sreekrishna, KD, James, CG, Rosemary, SS. Lipomatosis of the neck: case report and literature review. Int J Pediatr Otorhinolaryngol Extra 2010;5:39–41Google Scholar
14González-García, R, Rodríguez-Campo, FJ, Sastre-Pérez, J, Muñoz-Guerra, MF. Benign symmetric lipomatosis (Madelung disease): case report and current management. Aesthetic Plast Surg 2004;28:108–12CrossRefGoogle ScholarPubMed
15Zeitler, H, Ulrich-Merzenich, G, Richter, DF, Vetter, H, Walger, P. Multiple benign symmetric lipomatosis – a differential diagnosis of obesity. Is there a rationale for fibrate treatment? Obes Surg 2008;18:1354–6CrossRefGoogle Scholar