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Indolent mucormycosis of the paranasal sinus in immunocompetent patients: are antifungal drugs needed?

Published online by Cambridge University Press:  13 August 2013

H Jung  and
S K Park
H Jung
Affiliation:
Department of Otorhinolaryngology-Head and Neck Surgery, Inje University School of Medicine, Busan Paik Hospital, Busan, South Korea
S K Park*
Affiliation:
Department of Otorhinolaryngology-Head and Neck Surgery, Inje University School of Medicine, Busan Paik Hospital, Busan, South Korea
*
Address for correspondence: Dr Seong Kook Park, Department of Otorhinolaryngology-Head and Neck Surgery, Inje University, School of Medicine, Busan Paik Hospital, 633-165 Keakeum-dong, Busanjin-Ku, Busan 614-735, South Korea Fax: +82 51 892 3831 E-mail: sinus4@paik.ac.kr
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Abstract

Objective:

To report the clinical characteristics and treatment outcomes of indolent paranasal mucormycosis in immunocompetent individuals.

Materials and methods:

A retrospective review of four immunocompetent patients with indolent mucormycosis of the paranasal sinus managed by endoscopic sinus surgery only was performed. One year of regular follow up comprised angled endoscopy and repeated paranasal sinus computed tomography three months after surgery.

Results:

Clinical symptoms were non-specific. Pre-operative paranasal sinus computed tomography showed opacification of the unilateral maxillary sinus with focal calcification but without bony destruction or extension to the orbit or cranium. All patients underwent endoscopic sinus surgery without administration of antifungal agents. There was no recurrence on regular clinical and radiological follow up.

Conclusion:

For indolent paranasal mucormycosis in immunocompetent patients, endoscopic sinus surgery can be the treatment of choice, and the administration of antifungal drugs may not be necessary.

Keywords

MucormycosisParanasal SinusesAmphotericin BSurgical Procedures, OperativeImmunocompetence
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 127 , Issue 9 , September 2013 , pp. 872 - 875
Copyright
Copyright © JLO (1984) Limited 2013 

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