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Immunohistochemical findings of IgG recognized in the planum semilunatum of the guinea pig

Published online by Cambridge University Press:  29 June 2007

Minoru Ikeda  and
Claus Morgenstern
Minoru Ikeda*
Affiliation:
Department of Otolaryngology, Nihon University School of Medicine, Itabashi-ku, Tokyo, Japan.
Claus Morgenstern
Affiliation:
Department of Otolaryngology, Krankenhaus St. Georg, Hamburg, Germany.
*
Minoru Ikeda, M.D., Department of Otolargynology, Ninon University School of Medicine, 30-1 Oyaguchi, Itabashi-ku, Tokyo 173, Japan
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Abstract

The planum semilunatum is located on the lateral side of the crista ampullaris of thesemicircular canal. With regard to the functions of the planum semilunatum, some researchers assume the existence of secretory activity based on the microstructural features observed in isotopic experiments. In the present study, in order to confirm the existence of an immunological mechanism in the ampulla of the semicircular canal, the distribution of immunoglobulins in the semi-circular canal of guinea pigs was investigated immunohistochemically. Positivity of IgG wasobserved in the constituent cells of the planum semilunatum or beneath the basement membrane ofthe cells.It is concluded that ample IgG, which is an important constituent of the body fluids, is collected within this region. The planum semilunatum containing such ample amounts of IgG might be involved in the immunological mechanism operating in the ampullar of the semicircular canal.

Keywords

ImmunohistochemistryVestibuleGuinea pigs
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 106 , Issue 2 , February 1992 , pp. 93 - 97
Copyright
Copyright © JLO (1984) Limited 1992

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