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Expression of Fos-protein activated by tactile stimulation on the laryngeal vestibulum in the cat's lower brain stem

Published online by Cambridge University Press:  29 June 2007

Yasumasa Tanaka ,
Yoshikazu Yoshida  and
Minoru Hirano
Yasumasa Tanaka*
Affiliation:
Department of Otorhinolaryngology and Head and Neck Surgery, School of Medicine, Kurume University, Kurume, Japan.
Yoshikazu Yoshida
Affiliation:
Department of Otorhinolaryngology and Head and Neck Surgery, School of Medicine, Kurume University, Kurume, Japan.
Minoru Hirano
Affiliation:
Department of Otorhinolaryngology and Head and Neck Surgery, School of Medicine, Kurume University, Kurume, Japan.
*
Address for correspondence: Yasumasa Tanaka, M.D., Department of Otorhinolaryngology and Head and Neck Surgery, School of Medicine, Kurume University, 67 Asahimachi, Kurume, 830, Japan Fax: 81-942-37-1200.
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Abstract

To demonstrate morphologically the neurons participating in the4aryngeal reflex, Fos-expression, activated with tactile stimulation of the laryngeal vestibulum, was mapped in the cat's lower brain stem utilizing immunohistochemistry. In the stimulation group, many Fos-immunoreactive (ir) neurons were recognized in the nucleus tractus solitarii (NTS) from the level of the most rostral portion of the dorsal motor nucleus of the vagus to the level of the most caudal portion of the inferior olivary nucleus (IO), and in the nucleus ambiguus (NA) from the level of the rostral end of the hypoglossal nucleus to the level of the caudal end of the IO, bilaterally. While some Fos-ir cells were found in the spinal nucleus of the trigeminus, they were also found in the reticular nuclei bilaterally. In the control group, Fos-ir cells were distinctly fewer in number than those in the stimulation group. The results suggested that in the brain stem, the laryngeal reflex pathways have more than two synaptic relays through the interneurons in between the NTS and the NA.

Keywords

Proto-oncogene proteins c-FosImmunohistochemistryStimulation, tactileBrain stemCat
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 109 , Issue 1 , January 1995 , pp. 39 - 44
Copyright
Copyright © JLO (1984) Limited 1995

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