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The effects of nasal irrigation with various solutions after endoscopic sinus surgery: systematic review and meta-analysis

Published online by Cambridge University Press:  02 August 2018

X Z Chen ,
S Y Feng ,
L H Chang ,
X P Lai ,
X H Chen ,
Xia Li  and
G H Zhang
X Z Chen
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
S Y Feng
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai, China
L H Chang
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
X P Lai
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
X H Chen
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
Xia Li
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
G H Zhang*
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China
*
Author for correspondence: Dr Gehua Zhang, Department of Otolaryngology – Head and Neck Surgery, Third Affiliated Hospital of Sun Yat-sen University, No. 600 Tianhe Road, Guangzhou 510630, China Fax: +86 020 8525 3045 E-mail: zhanggeh@mail.sysu.edu.cn
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Abstract

Background

Nasal irrigation is commonly performed in patients with chronic rhinosinusitis after functional endoscopic sinus surgery. This study systematically assessed the clinical efficacy of nasal irrigation from the medical literature.

Methods

The PubMed, Embase and Cochrane Central Register of Controlled Trials databases were searched using a comprehensive strategy, limited to English-language articles, published from October 1971 to March 2017, and comprising human subjects.

Results

A total of 824 trials were identified, 5 of which, involving 331 participants, were included in this systematic review. After selection, only three trials were eligible for inclusion in a meta-analysis. Nasal irrigation using normal saline and various solutions was found to be effective in reducing symptom scores and endoscopic scores for chronic rhinosinusitis patients after functional endoscopic sinus surgery. Comparison of outcome measures, such as eosinophil count reduction, revealed that various solutions are more effective than normal saline alone; however, no statistical significance was found in terms of reduced symptom or endoscopic scores.

Conclusion

Based on the current limited evidence, nasal irrigation is an effective therapy for chronic rhinosinusitis patients after functional endoscopic sinus surgery. However, when comparing various solutions with normal saline, no significant difference was found in symptom scores or endoscopic scores.

Keywords

Nasal LavageChronic SinusitisSaline SolutionSodium ChlorideEndoscopy
Type
Review Articles
Information
The Journal of Laryngology & Otology , Volume 132 , Issue 8 , August 2018 , pp. 673 - 679
Copyright
Copyright © JLO (1984) Limited, 2018 

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Footnotes

Dr G Zhang takes responsibility for the integrity of the content of the paper

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