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An unusual presentation of aggressive epithelial-myoepithelial carcinoma of the nasal cavity with high-grade histology

Published online by Cambridge University Press:  05 September 2011

J-O Park ,
C-K Jung ,
D-I Sun  and
M-S Kim
J-O Park
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul, South Korea
C-K Jung
Affiliation:
Department of Hospital Pathology, College of Medicine, The Catholic University of Korea, Seoul, South Korea
D-I Sun
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul, South Korea
M-S Kim*
Affiliation:
Department of Otolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul, South Korea
*
Address for correspondence: Dr Min-Sik Kim, Department of Otolaryngology-HNS, 505 Banpodong SeochoguSeoul St Mary's Hospital, The Catholic University of Korea, Seoul, South Korea137-040 Fax: +82 2 595 1354 E-mail: entkms@catholic.ac.kr
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Abstract

Background:

Epithelial-myoepithelial carcinoma is an uncommon, low-grade carcinoma that generally occurs in the salivary glands. A few cases of epithelial-myoepithelial carcinoma arising in the nasal cavity have been reported. We describe a unique case of aggressive epithelial-myoepithelial carcinoma in the nasal cavity.

Case report:

A 36-year-old woman presented with a mass in her left nasal cavity. Histopathological evaluation revealed it to be an epithelial-myoepithelial carcinoma with overt nuclear atypia, frequent mitoses and necrosis. The tumour recurred in the contralateral nasal cavity 15 months following primary excision. Medial maxillectomy and radiation therapy were performed. Seven-month follow up revealed extensive bone metastases.

Conclusion:

We report a rare case of aggressive epithelial-myoepithelial carcinoma in the nasal cavity, with high-grade histology.

Keywords

Myoepithelial TumourCarcinomaNasal CavityMetastasis
Type
Clinical Records
Information
The Journal of Laryngology & Otology , Volume 125 , Issue 12 , December 2011 , pp. 1286 - 1289
Copyright
Copyright © JLO (1984) Limited 2011

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