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Serum immunoglobulin E levels in patients with head and neck cancer

Published online by Cambridge University Press:  29 June 2007

Harbans Lal ,
Bharat Singh ,
Umesh Wig  and
A. S. Saini
Harbans Lal*
Affiliation:
Departments of Biochemistry, Rohtak, India.
Bharat Singh
Affiliation:
ENT Medical College, Rohtak, India.
Umesh Wig
Affiliation:
ENT Medical College, Rohtak, India.
A. S. Saini
Affiliation:
ENT Medical College, Rohtak, India.
*
Dr. Harbans Lal, Department of Biochemistry, 12/9J, Medical College, Rohtak-124001, India.
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Abstract

Serum immunoglobulin E levels were estimated in 50 patients with head and neck cancer and in 25 controls. Mean serum IgE value was significantly higher in patients with various sites of cancer in the head and neck region other than carcinoma of the tonsil. The levels increased with advancement in the stage of cancer. There was, however, no difference in mean serum IgE value with respect to the character of the lesion, to the histopathological type of growth or to radiotherapy.

In patients with carcinoma of the tonsil, the mean serum IgE concentration was significantly lowered.

Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 102 , Issue 5 , May 1988 , pp. 432 - 434
Copyright
Copyright © JLO (1984) Limited 1988

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References

Augustin, R. and Chandradasa, K. D. (1971) IgE levels and allergic skin reactions in cancer and non-cancer patients. International Archives of Allergy, 41: 141–143.CrossRefGoogle ScholarPubMed
Eastham, R. J., Mason, J. M. and Jennings, B. R. (1976) T-cell rossette test in squamous cell carcinoma of the head and neck. Archives of Otolaryngology, 102: 171–175.CrossRefGoogle Scholar
Engvall, E. and Perlman, P. (1972) Enzyme-linked immunosor-bent assay, ELISA, III. Quantitation of specific antibodies enzyme-labelled anti-immuno-globulin in antigen-coated tubes. Journal of Immunology, 109: 129–135.CrossRefGoogle Scholar
Jacobs, A., Joynson, D. H. M., Walker, D. M. and Dolby, A. E. (1972) Circulating levels of immunoglobulin E in patients with cancer. Lancet, 2: 1059–1061.CrossRefGoogle ScholarPubMed
Katz, A. E. (1980) Advances in the immunology of head and neck cancer. Otolaryngological Clinics of North America, 13: 431–436.CrossRefGoogle ScholarPubMed
Okumara, K. and Tada, T. (1971) Regulation of homocytotropic antibody formation in the rat. 3. Effect of thymectomy and spleenectomy. Journal of Immunology, 106: 1019–1025.CrossRefGoogle Scholar
O'Neill, P. A. and Romsdahl, M. (1974) IgA as a blocking factor in human malignant melanoma. Immunol. Commun., 3: 427–438.CrossRefGoogle ScholarPubMed
Rubinstein, E., Reisman, R. E., Sokal, J. E. and Arbesman, C. E. (1975) Relationship of serum total IgE and cell mediated immunity in patients with Hodgkin's disease. Journal of Allergy and Clinical Immunology, 55: 115.Google Scholar
Salmon, S. E. (1973) Immunoglobulin synthesis and tumor kinetics of multiple myeloma. Seminars in Hematology, 10: 135–147.Google ScholarPubMed
Scully, C. (1982) Immunological abnormalities in oral carcinoma and oral keratosis. Journal of Maxillo-Facial Surgery, 10: 113–115.CrossRefGoogle ScholarPubMed
Serrou, B., Dubosis, J. B. and Robinet-Levy, M. (1975) IgE serum levels in cancer patients. Lancet, 1: 396–397.CrossRefGoogle Scholar
Sipos, J., Gabor, V. and Toth, Z. (1978) Inhibition of leuckocyte migration by tumor-associated antigen and its modification by serum; IgA as a blocking factor. Neoplasms, 25: 181–188.Google Scholar
UICC (1978) Report of Committee on TNM Classification: Geneva.Google Scholar
Vijayakumar, T., Ankhathil, K., Remani, P., Sasidharan, V. K., Vijayan, K. K. and Vasudevan, D. M. (1986) Serum immu-noglobulins in patients with carcinoma of the oral cavity, Uterine cervix and breast cancer. Immunology and Immunotherapy, 22: 76–79.Google Scholar
Waldman, T. A., Bull, J. M., Bruce, R. M., Broder, S., Jost, M. C, Balestra, S. T. and Suer, M. E. (1974) Serum immunoglobulin E levels in patients with neoplastic disease. Journal of Immunology, 113: 379–386.CrossRefGoogle Scholar
Wells, J. V. (1976) Basic and Clinical Immunology. Metabolism of Immunoglobulins. Asian Maruzen Edition, pp. 195–203.Google Scholar
Wig, U., Sani, A. S. and Gupta, V. K. (1983) E-rosette forming cells (E-RFC) in squamous cell carcinoma of the larynx and laryngopharynx. Journal of Laryngology and Otology, 97: 527–530.CrossRefGoogle ScholarPubMed