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Impact of pre-operative body mass index in head and neck cancer patients undergoing microvascular reconstruction

Published online by Cambridge University Press:  02 October 2017

D-J Hyun ,
Y-H Joo  and
M-S Kim
D-J Hyun
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, GNG Hospital, Seoul, Republic of Korea
Y-H Joo
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, College of Medicine, Catholic University of Korea, Seoul, Republic of Korea
M-S Kim*
Affiliation:
Department of Otolaryngology – Head and Neck Surgery, College of Medicine, Catholic University of Korea, Seoul, Republic of Korea
*
Address for correspondence: Dr Min-Sik Kim, Department of Otolaryngology – Head and Neck Surgery, 505 Banpodong Seochogu, Seoul St Mary's Hospital, Catholic University of Korea, Seoul 137-040, Republic of Korea E-mail: entkms@catholic.ac.kr
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Abstract

Objectives:

To analyse the relationship of pre-operative body mass index with surgical complications and oncological outcomes in patients undergoing microvascular reconstruction for head and neck squamous cell cancer.

Method:

A retrospective review was conducted of 259 patients who underwent microvascular free flap reconstruction after head and neck ablative surgery.

Results:

Mean body mass index was 22.48 kg/m2. There were no correlations between body mass index and: flap failure (p = 0.739), flap ischaemia (p = 0.644), pharyngocutaneous fistula (p = 0.141) or wound infection (p = 0.224). The five-year disease-specific survival rate was 63 per cent. On univariate analysis, the five-year disease-specific survival rate was significantly correlated with pre-operative body mass index, based on Kaplan–Meier survival curves (p = 0.028). The five-year disease-specific survival rates in underweight, normal weight, overweight and obese groups were 47 per cent, 55 per cent, 65 per cent and 80 per cent, respectively.

Conclusion:

Pre-operative body mass index was a useful predictor for recurrence and survival in patients who underwent microvascular reconstruction for head and neck squamous cell cancer.

Keywords

Squamous Cell CarcinomaHead And Neck NeoplasmsBody Mass IndexReconstructive Surgical ProcedureSurvival
Type
Main Articles
Information
The Journal of Laryngology & Otology , Volume 131 , Issue 11 , November 2017 , pp. 972 - 976
Copyright
Copyright © JLO (1984) Limited 2017 

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