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Transmission electron microscopical studies of the site of attachment of Ancylostoma ceylanicum To the small bowel mucosa of the dog

Published online by Cambridge University Press:  05 June 2009

S. M. Carroll ,
T. A. Robertson ,
J. M. Papadimitriou  and
D. I. Grove
S. M. Carroll
Affiliation:
Departments of Medicine and Pathology, University of Western Australia, Queen Elizabeth II Medical Centre, Perth, Western Australia 6009
T. A. Robertson
Affiliation:
Departments of Medicine and Pathology, University of Western Australia, Queen Elizabeth II Medical Centre, Perth, Western Australia 6009
J. M. Papadimitriou
Affiliation:
Departments of Medicine and Pathology, University of Western Australia, Queen Elizabeth II Medical Centre, Perth, Western Australia 6009
D. I. Grove
Affiliation:
Departments of Medicine and Pathology, University of Western Australia, Queen Elizabeth II Medical Centre, Perth, Western Australia 6009
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Abstract

The host-parasite interaction at the site of attachment of the adult hookworm, Ancylostoma ceylanicum, to the small bowel mucosa of the dog has been examined by transmission electron microscopy. The lamina propria around the heads of the worms showed intense infiltration with neutrophilic and cosinophilic leucocytes, and plasma cells were also prominent. Erythrocytcs were cxtravasatcd within the lamina propria while the portions of mucosa engulfed into the buccal cavities of the worms were nccrotic and included aggregates of collagen fibres. Within the lumina of the worms were erythrocytcs in varying stages of lysis together with other nccrotic debris.The mucous membrane adjacent to the heads of the worms was ulcerated while more distant cntcrocytcs were small, distorted and displayed various degrees of microvillar loss. Many mucosal blood vessels had platelet aggregates within their iumina but no fibrin deposition was observed. Vessels were often seen in the bases of the ulcers and were prone to rupture. Erythrocytcs and leucocytes were seen in the dog intestinal lumen in close proximity to the bodies of the worms.

Type
Research Article
Information
Journal of Helminthology , Volume 58 , Issue 4 , December 1984 , pp. 313 - 320
Copyright
Copyright © Cambridge University Press 1984

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References

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