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The site selected by the larvae of Heligmosomoides polygyrus

Published online by Cambridge University Press:  18 November 2009

M. V. K. Sukhdeo
Affiliation:
Institute of Parasitology, McGill University, Macdonald College, Ste. Anne de Bellevue, Quebec, H9X ICO Canada
R. T. O'Grady
Affiliation:
Institute of Parasitology, McGill University, Macdonald College, Ste. Anne de Bellevue, Quebec, H9X ICO Canada
S. C. Hsu
Affiliation:
Institute of Parasitology, McGill University, Macdonald College, Ste. Anne de Bellevue, Quebec, H9X ICO Canada

Abstract

Histological examination of the small intestine of mice infected with Heligmosomoides polygyrus indicates that the final site of the larvae is in the circular muscle layer of the muscularis externa of the anterior small intestine. The larvae become embedded in the muscle between the first and third days after infection and are subsequently sequestered by a localized leucocytic response. There is no evidence of a true cyst. Histological evidence suggests that the larvae actively feed on the tissues of the host during their development.

Type
Research Note
Copyright
Copyright © Cambridge University Press 1984

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References

REFERENCES

Bryant, V. (1973) The life cycle of Nematospiroides dubius Baylis, 1926 (Nematoda: Heligmosomidae). Journal of Helminthology, 47, 263268.Google Scholar
Carleton, H.M. (1962) Histological technique. Oxford University Press, London.Google Scholar
Ehrenford, F.D. (1954) The life cycle of Nematospiroides dubius Baylis (Nematoda: Heligmosomidae). Journal of Parasitology, 40, 480481.Google Scholar
Fahmy, M.A.M. (1956) An investigation on the life cycle of Nematospiroides dubius (Nematoda: Heligmosomidae) with special reference to the free-living stages. Zeitschrift für Parasitenkunde, 17, 393399.CrossRefGoogle Scholar
Humason, G.L. (1972) Animal tissue techniques. 3rd edit. W.H. Freeman and Company,San Francisco.Google Scholar
Liu, S. (1965) Pathology of Nematospiroides dubius. I. Primary infections in C3H and Webster mice. Experimental Parasitology, 17, 123135.CrossRefGoogle ScholarPubMed
Mccoy, O.R., Downing, V.F. & Van Voorkis, S.N. (1941) The penetration of radioactive phosphorus into encysted Trichinella larvae. Journal of Parasitology, 27, 5358.Google Scholar
Rutherford, T.A. & Webster, J.M. (1974) Transcuticular uptake of glucose by the entomophilic nematode, Mermis nigrescens. Journal of Parasitology, 60, 804808.CrossRefGoogle ScholarPubMed
Rutherford, T.A., Webster, J.M. & Barlow, S.J. (1977) Physiology and nutrient uptake by the entomophilic nematode, Mermis nigrescens (Mermithidae). Canadian Journal of Zoology, 55, 17731781.Google Scholar
Sommerville, R.I. & Bailey, M.A. (1973) Nematospiroides dubius: exsheathment of infective juveniles. Experimental Parasitology, 33, 19.CrossRefGoogle ScholarPubMed
Spurlock, G.M. (1943) Observations on host-parasite relations between laboratory mice and Nematospiroides dubius Baylis. Journal of Parasitology, 29, 303311.CrossRefGoogle Scholar
Stoner, R.D. & Hankes, L.V. (1955) Incorporation of C14-labelled amino acids by Trichinella spiralis larvae. American Journal of Hygiene, 10, 384418.Google Scholar
Stoner, R.D. & Hankes, L.V. (1958) In vitro metabolism of DL-tyrosine-2-C-14 and DL-tryptophan-2-C-14 by Trichinella spiralis. Experimental Parasitology, 7, 145151.CrossRefGoogle ScholarPubMed
Sukhdeo, M.V.K. (1981) Studies on site selection of some gastrointestinal nematodes. Ph.D. Thesis, McGill University, Montreal.Google Scholar
Sukhdeo, M.V.K. & Croll, N.A. (1981) The location of parasites within their hosts: bile and the site selection behaviour of Nematospiroides dubius. International Journal for Parasitology, 11, 157162.CrossRefGoogle ScholarPubMed