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A Modified Technique for Preliminary Screening of Compounds for Anthelmintic Activity against Eggs and Larvae of Bursate Nematodes of Sheep

Published online by Cambridge University Press:  18 November 2009

I. W. Parnell
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Extract

A technique is described for measuring the larvicidal activity of compounds against the free-living stages of bursate nematodes of sheep. Cultures were made in small glass tubes in 2 oz. “pomade” jars, and the larvicidal effects of the compounds were measured by comparing the number of infective larvae which were recovered from treated cultures with the numbers from the control cultures.

This technique provides another in vitro screening method for compounds which may be effective as anthelmintics against bursate nematodes.

Type
Research Papers
Information
Journal of Helminthology , Volume 38 , Issue 1-2 , June 1964 , pp. 47 - 56
Copyright
Copyright © Cambridge University Press 1964

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References

Castle, E. J., 1956.—“The rate of passage of foodstuffs through the alimentary tract of the goat. 1. Studies on adult animals fed on hay and concentrates” Brit J. Nutr., 10, 15–23.CrossRefGoogle ScholarPubMed
Kauzal, G. P. and Gordon, H.McL., 1941.—“A useful mixing apparatus for the preparation of suspensions of faeces for helminthological examinations”. J. Conn. set. industr. lies. Aust., 14, 304–305.Google Scholar
Levine, N. D., 1950.—“The use of horse strongyle larvae in screening compounds for anthelmintic activity”. Trans. III. Acad. Set., 43, 233–236.Google Scholar
Mackie, A. and Parnell, I. W., 1955.—“Comparison of the results of four in vitro anthelmintic testing techniques”. J. Pharm. Lond., 7, 416–420.Google Scholar
Parnell, I. W., 1936.—“Studies on the bionomics and control of the bursate nematodes of horses and sheep. II. Technique”. Canad. J. lies., D, 14, 71–81.CrossRefGoogle Scholar
Parnell, I. W., and Mackie, A., 1952.—“Some observations on the lethal effects of various chemicals against the free living stages of Sclcrostomcs (Nematoda)”. Brit. J. Pharmacol., 7, 509–533.Google ScholarPubMed
Silvkrman, P. H., 1959.—“In vitro cultivation of the histotrophic stages of Haemonchus contortus and Ostertagia spp.” Nature, Lond., 183, 197.CrossRefGoogle Scholar
Weinstein, P. P. and Jones, M. F., 1950.—“The in vitro cultivation of Nippostrongylus muris to the adult stage”. J. Parasit., 42, 215–236.CrossRefGoogle Scholar
Weinstein, P. P., Jones, M. F., 1957.—“The development of a study on the axenic growth in vitro of Nippostrongylus muris to the adult stage”. Amer. J. trop. Med., 6, 480–484.CrossRefGoogle Scholar
Whitlock, H. V., 1950.—“An improved method for the culture of ncmatodc larvae in sheep faeces”. Aust. vet. J., 32, 141–143.CrossRefGoogle Scholar