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Cestocidal activity of Acacia auriculiformis

Published online by Cambridge University Press:  05 June 2009

N.K. Ghosh
Affiliation:
Department of Zoology, Visva-Bharati University, Santiniketan-731235, West Bengal, India
S.P. Sinha Babu
Affiliation:
Department of Zoology, Visva-Bharati University, Santiniketan-731235, West Bengal, India
N.C. Sukul
Affiliation:
Department of Zoology, Visva-Bharati University, Santiniketan-731235, West Bengal, India
A. Ito
Affiliation:
Department of Parasitology, Gifu University School of Medicine, Gifu City 500, Japan

Abstract

The cestocidal activity of Acacia auriculiformis was evaluated using rats each harbouring a single adult worm of Hymenolepis diminuta. The ethanol extract (300 mg/kg/day) and the saponins (200 mg/kg/day) obtained from the funicles of A. auriculiformis, were administered orally to two groups each of 10 rats, respectively, on day 20 after oral inoculation with a single cysticercoid of H. diminuta. Adult worms were expelled within 5 days from rats treated with the ethanol extract and within 3 days from those treated with saponins. No appreciable side effects were observed in the treated rats.

Type
Research Note
Copyright
Copyright © Cambridge University Press 1996

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References

Chatterjee, A. & Sukul, N.C. (1981) Nematicidal action of three wild plants. Nematologica 26, 500502.Google Scholar
Chatterjee, R.K., Fatma, N., Murthy, P.K., Sinha, P., Kulshrestha, D.K. & Dhawan, B.N. (1992) Macro-filaricidal activity of the stembark of Streblus asper and its major active constituents. Drug Development Research 26, 112.CrossRefGoogle Scholar
Ghosh, M., Sinha, Babu S.P., Sukul, N.C. & Mahato, S.B. (1993) Antifilarial effect of two triterpenoid saponins isolated from Acacia auriculiformis. Indian Journal of Experimental Biology 31, 604606.Google ScholarPubMed
Ghosh, M., Sinha, Babu S.P., Sukul, N.C., Sahu, N.P. & Mahato, S.B. (1994) Antifilarial effect of solamargine isolated from Solanum khasianum. International Journal of Pharmacognosy 32 (2), 184190.CrossRefGoogle Scholar
Ito, A. & Onitake, K. (1987) Hymenolepis diminuta and H. nana: Cross immunity against the lumen phase in BALB/c mice. Experimental Parasitology 64, 4852.CrossRefGoogle Scholar
Mahato, S.B., Pal, B.C. & Nandy, A.K. (1992) Structure elucidation of two acylated triterpenoid bis-glycosides from Acacia auriculiformis Cunn. Tetrahedron 48, 67176728.CrossRefGoogle Scholar