Unsteady boundary-layer development over moving walls in the limit of infinite Reynolds number is investigated using both the Eulerian and Lagrangian formulations. To illustrate general trends, two model problems are considered, namely the translating and rotating circular cylinder and a vortex convected in a uniform flow above an infinite flat plate. To enhance computational speed and accuracy for the Lagrangian formulation, a remeshing algorithm is developed. The calculated results show that unsteady separation is delayed with increasing wall speed and is eventually suppressed when the speed of the separation singularity approaches that of the local mainstream velocity. This suppression is also described analytically. Only ‘upstream-slipping’ separation is found to occur in the model problems. The changes in the topological features of the flow just prior to the separation that occur with increasing wall speed are discussed.