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Studies on antimutagenic effect of milk cultured with lactic acid bacteria on the Trp-P2-induced mutagenicity to TA98 strain of Salmonella typhimurium

Published online by Cambridge University Press:  01 June 2009

M. Hosoda
Affiliation:
Technical Research Laboratory, Takanashi Milk Products Co. Ltd, Yokohama, Kanagawa-ken 241, Japan
H. Hashimoto
Affiliation:
Technical Research Laboratory, Takanashi Milk Products Co. Ltd, Yokohama, Kanagawa-ken 241, Japan
H. Morita
Affiliation:
Technical Research Laboratory, Takanashi Milk Products Co. Ltd, Yokohama, Kanagawa-ken 241, Japan
M. Chiba
Affiliation:
Technical Research Laboratory, Takanashi Milk Products Co. Ltd, Yokohama, Kanagawa-ken 241, Japan
A. Hosono
Affiliation:
Technical Research Laboratory, Takanashi Milk Products Co. Ltd, Yokohama, Kanagawa-ken 241, Japan Faculty of Agriculture, Shinshu University, Minamiminowa-mura, Nagano-ken 399-45, Japan

Summary

The inhibitory effects of cultured milk using 76 strains of lactic acid bacteria isolated from milk products were investigated on the mutagenicity of 3-amino-1-methyl-5H-pyrido[4,3−b]indole (Trp-P2), a tryptophan pyrolysate for Salmonella typhimurium TA98. Each cultured milk sample displayed its characteristic antimutagenic effect against the mutagenicity of Trp-P2. The milk cultured with Lactobacillus acidophilus LA106 (LA2) showed the highest inhibition of 82·1% among the strains used. Milk samples cultured with Lactococcus lactis subsp. lactis, L11103 (10−3) and L11102 (KM) also exhibited higher inhibition percentages.

Type
Original Articles
Copyright
Copyright © Proprietors of Journal of Dairy Research 1992

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