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Divergence at the casein haplotypes in dairy and meat goat breeds

Published online by Cambridge University Press:  05 November 2009

Julia Küpper ,
Stefania Chessa ,
Daniela Rignanese ,
Anna Caroli  and
Georg Erhardt
Julia Küpper
Affiliation:
Institut für Tierzucht und Haustiergenetik, Justus-Liebig-Universität, Ludwigstraße 21b, 35390Gießen, Germany
Stefania Chessa
Affiliation:
Dipartimento di Scienze e Tecnologie Veterinarie per la Sicurezza Alimentare, Università degli Studi di Milano, Via Trentacoste 2, 20134Milano, Italy
Daniela Rignanese
Affiliation:
Dipartimento di Scienze e Tecnologie Veterinarie per la Sicurezza Alimentare, Università degli Studi di Milano, Via Trentacoste 2, 20134Milano, Italy
Anna Caroli
Affiliation:
Dipartimento di Scienze Biomediche e Biotecnologie, Università degli Studi di Brescia, Viale Europa 11, 5123Brescia, Italy
Georg Erhardt*
Affiliation:
Institut für Tierzucht und Haustiergenetik, Justus-Liebig-Universität, Ludwigstraße 21b, 35390Gießen, Germany
*
*For correspondence; e-mail: Georg.Erhardt@agrar.uni-giessen.de
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Abstract

Casein genes have been proved to have an influence on milk properties, and are in addition appropriate for phylogeny studies. A large number of casein polymorphisms exist in goats, making their analysis quite complex. The four casein loci were analyzed by molecular techniques for genetic polymorphism detection in the two dairy goat breeds Bunte Deutsche Edelziege (BDE; n=96), Weiße Deutsche Edelziege (WDE; n=91), and the meat goat breed Buren (n=75). Of the 35 analyzed alleles, 18 were found in BDE, and 17 in Buren goats and WDE. In addition, a new allele was identified at the CSN1S1 locus in the BDE, showing a frequency of 0·05. This variant, named CSN1S1*A′, is characterized by a t→c transversion in intron 9. Linkage disequilibrium was found at the casein haplotype in all three breeds. A total of 30 haplotypes showed frequencies higher than 0·01. In the Buren breed only one haplotype showed a frequency higher than 0·1. The ancestral haplotype B-A-A-B (in the order: CSN1S1-CSN2-CSN1S2-CSN3) occurred in all three breeds, showing a very high frequency (>0·8) in the Buren.

Keywords

casein complexmeat goatCSN1S1*A′haplotypes
Type
Research Article
Information
Journal of Dairy Research , Volume 77 , Issue 1 , February 2010 , pp. 56 - 62
Copyright
Copyright © Proprietors of Journal of Dairy Research 2009

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