Hostname: page-component-77c89778f8-vsgnj Total loading time: 0 Render date: 2024-07-20T18:47:59.088Z Has data issue: false hasContentIssue false
  • English
  • Français

Changes in phosphorus metabolism of sheep in response to the increased demands for P associated with an intravenous infusion of calcium

Published online by Cambridge University Press:  27 March 2009

G. D. Braithwaite
G. D. Braithwaite
Affiliation:
National Institute for Research in Dairying, Shinfield, Reading, RG2 9AT
Get access Rights & Permissions [Opens in a new window]

Summary

The effect on phosphorus and calcium metabolism of a high rate of Ca infused directly into the blood of 10-month-old sheep, already receiving an adequate Ca and P intake, has been studied by a combination of balance and radioisotope techniques. Ca retention was significantly increased during the infusion and most of the extra Ca was retained in bone. Urinary Ca excretion also showed a small but significant increase and the efficiency of Ca absorption a small but significant decrease. Because of the close association of Ca and P in bone, the increased skeletal retention of Ca resulted in an increased skeletal P retention and hence an increased demand for P. This increased P demand was met partly by a decrease in the rate of endogenous faecal loss of P and partly by an increase in the rate and efficiency of P absorption. Because the increase in P demand was relatively small, it was not possible to decide whether the endogenous faecal loss of P can be reduced in response to increased demands to the level found at zero P intake as suggested by the Agricultural Research Council (1980) or whether higher losses at normal P intakes are inevitable.

Type
Research Article
Information
The Journal of Agricultural Science , Volume 102 , Issue 1 , February 1984 , pp. 135 - 139
Copyright
Copyright © Cambridge University Press 1984

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Agricultural Research Council (1980). The Nutrient Requirements of Ruminant Livestock. Slough: Commonwealth Agricultural Bureaux.Google Scholar
Aubert, J.-P. & Milhaud, G. (1960). Méthode de mesure des principles voies du métabolisme calcique chez l'homme. Biochimica et Biophysica Acta 39, 122–139.CrossRefGoogle Scholar
Braithwaite, G. D. (1974). The effect of changes of dietary calcium concentration on calcium metabolism in sheep. British Journal of Nutrition 31, 319–331.CrossRefGoogle ScholarPubMed
Braithwaite, G. D. (1975). Studies on the absorption and retention of calcium and phosphorus by young and mature Ca-deficient sheep. British Journal of Nutrition 34,311–324.CrossRefGoogle Scholar
Braithwaite, G. D. (1978). Adaptations in the calcium and phosphorus metabolism of sheep in response to an intravenous infusion of Ca. British Journal of Nutrition 40, 17–21.CrossRefGoogle Scholar
Braithwaite, G. D. (1979). The effect of dietary intake of calcium and phosphorus on their absorption and retention by mature Ca-replete sheep. Journal of Agricultural Science, Cambridge 92, 337–342.CrossRefGoogle Scholar
Braithwaite, G. D. (1980). The effect of dose rate of 1-α-hydroxycholecalciferol on calcium and phosphorus metabolism in sheep. British Journal of Nutrition 44, 183–191.CrossRefGoogle ScholarPubMed
Braithwaite, G. D. (1981). Effect of 1-α-hydroxycholecalciferol on calcium and phosphorus metabolism in sheep given high or low calcium diets. Journal of Agricultural Science, Cambridge 96, 291–299.CrossRefGoogle Scholar
Braithwaite, G. D. (1983). Calcium and phosphorus requirements of the ewe in pregnancy and lactation. 2. Phosphorus. British Journal of Nutrition (in the Press).Google ScholarPubMed
Braithwaite, G. D., Glascock, R. F. & Riazuddin, Sh. (1969). Calcium metabolism in lactating ewes. British Journal of Nutrition 23, 827–834.CrossRefGoogle ScholarPubMed
Braithwaite, G. D., Glascock, R. F. & Riazuddin, SH. (1970). Calcium metabolism in pregnant ewes. British Journal of Nutrition 24, 661–670.CrossRefGoogle ScholarPubMed
Braithwaite, G. D. & Riazuddin, Sh. (1971). The effect of age and level of dietary calcium intake on calcium metabolism in sheep. British Journal of Nutrilion 26, 215–225.CrossRefGoogle ScholarPubMed
Field, A. C, Coop, R. L., Dingwall, R. A. & Monroe, C. S. (1982). The phosphorus requirement for growth and maintenance of sheep. Journal of Agricultural Science, Cambridge 99, 311–317.CrossRefGoogle Scholar
Field, A. C, Sykes, A. R. & Gunn, R. G. (1974). Effects of age and state of incisor dentition on faecal output of dry matter and on faecal and urinary output of nitrogen and minerals, of sheep grazing hill pastures. Journal of Agricultural Science, Cambridge 83, 151–160.CrossRefGoogle Scholar
Grace, N. D. (1980). Effect of increasing phosphorus intake on the P faecal endogenous loss in the sheep. Proceedings of the New Zealand Society for Animal Production 40, 221–225.Google Scholar
Holick, M. F., Taleva, T. E., Holick, S. A., Schnoes, H. K., DeLuca, H. F. & Gallagher, B. M. (1976). Synthesis of l-α-hydroxy(6-3H)-vitamin D3 and its metabolism to lα,25-dihydroxy(6-3H)-vitamin D3 in the rat. Journal of Biological Chemistry 251, 1020–1024.CrossRefGoogle Scholar
Lueker, C. E. & Lofgreen, G. P. (1961). Effects of intake and calcium to phosphorus ratio on absorption of these elements by sheep. Journal of Nutrition 74, 233–238.CrossRefGoogle Scholar
Nel, J. W. & Moir, R. J. (1974). The effect of ruminal and duodenal application of different levels of calcium and phosphorus to sheep on semi purified diets. South African Journal of Animal Science 4, 1–20.Google Scholar
Preston, R. L. & Pfander, W. H. (1964). Phosphorus metabolism in lambs fed varying phosphorus intakes. Journal of Nutrition 83, 369–378.CrossRefGoogle ScholarPubMed
Sykes, A. R. & Dingwall, R. A. (1976). The phosphorus requirement of pregnant sheep. Journal of Agricultural Science, Cambridge 86, 587–594.CrossRefGoogle Scholar
Towns, K. M., Boston, R. C. & Leaver, D. D. (1978). The effect of intravenous administration of phosphorus on phosphorus and calcium metabolism in sheep. Australian Journal of Agricultural Research 29, 587–593.CrossRefGoogle Scholar
Young, V. R., Lofgreen, G. P. & Luick, J. R. (1966). The effects of phosphorus depletion, and of calcium and phosphorus intake, on the endogenous excretion of these elements by sheep. British, Journal of Nutrition 20, 795–805.CrossRefGoogle ScholarPubMed
Young, V. R., Richards, W. P. C., Lofgreen, G. P. & Luick, J. R. (1966). Phosphorus depletion in sheep and the ratio of calcium to phosphorus in the diet with reference to calcium and phosphorus absorption. British Journal of Nutrition 20, 783–794.CrossRefGoogle ScholarPubMed