Hostname: page-component-8448b6f56d-gtxcr Total loading time: 0 Render date: 2024-04-25T05:35:12.428Z Has data issue: false hasContentIssue false

Psychotropic drug regimes in compulsive water drinkers

Published online by Cambridge University Press:  13 June 2014

John A Cooney*
Affiliation:
University of Alberta, Clinical Head, Division of Geriatric Psychiatry, Department of Geriatrics, Edmonton General Hospital, 11111 Jasper Avenue, Edmonton. Alberta T5K 0L4., Canada

Abstract

Objective: To assess the importance of psychotropic medications in Compulsive Water Drinking (CWD) among psychiatric inpatients. Method: The psychotropic medication regimes of 21 CWD inpatients (16 of whom had a diagnosis of schizophrenia) and 21 age and sex matched control inpatients were compared. The CWD group was selected on the basis of urine specific gravity testing amongst the non-geriatric rehabilitation population of a Canadian psychiatric hospital. Regular and prn medications were compared by type and dose. Results: Both groups had generally similar regular medication regimes. No significant differences were found for any of the more commonly prescribed medications. There was a nonsignificant tendency for more CWD subjects to be given prn psychotropics, likely a consequence rather than a cause of the polydipsia. Conclusion: No significant differences were found between the two groups. However, because of the large number of medications used and the relatively small number of subjects, the study has relatively low power. A larger study, combining the CWD inpatients of several hospitals, would be required to definitely rule out a role for psychotropics in the aetiology of CWD.

Type
Original Papers
Copyright
Copyright © Cambridge University Press 1993

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Illowsky, BP, Kirch, DG. Polydipsia and hyponatremia in psychiatric patients. Am J Psychiatry 1988; 145: 675683.Google ScholarPubMed
2.Lee, S, Chow, CC, Koo, LCL. Altered state of consciousness in a compulsive water drinker. Br J Psychiatry 1989; 154: 556558.CrossRefGoogle Scholar
3.Berry, EM, Halon, D, Fainaru, M. Iatrogenic polydipsia. Lancet 1977; ii: 937938.CrossRefGoogle Scholar
4.Cooney, JA. Compulsive water drinking and water intoxication. Am J Psychiatry 1989; 146: 1235.Google ScholarPubMed
5.Dubrovsky, SL, Grabon, S, Berl, T, Schrier, RW. Syndrome of inappropriate secretion of antidiuretic hormone with exacerbated psychosis. Ann Intern Med 1973; 79: 551554.CrossRefGoogle Scholar
6.Jones, BD. Psychosis associated with water intoxication: psychogenic polydipsia or concomitant dopaminergic supersensitivity disorders? Lancet 1984; ii: 519520.CrossRefGoogle Scholar
7.Winstead, DK. Coffee consumption among psychiatric inpatients. Am J Psychiatry 1976; 133: 14471450.Google ScholarPubMed
8.Smith, WO, Clark, ML. Self-induced water intoxication in schizophrenic patients. Am J Psychaitry 1980; 137: 10551060.Google ScholarPubMed
9.Jose, CJ, Perez-Cruet, J. Incidence and morbidity of self-induced water intoxication in state mental hospital patients. Am J Psychiatry 1979; 136: 221222.Google ScholarPubMed
10.Blum, A, Tempey, FW, Lynch, WJ. Somatic findings in patients with psychogenic polydipsia. J Clin Psychiatry 1983; 44: 5556.Google ScholarPubMed
11.Cooney, JA. Compulsive water drinking, water intoxication and alcohol abuse. Ir J Psychol Med 1991; 8: 2225.CrossRefGoogle Scholar
12.Sandifer, MG. Hyponatremia due to psychotropic drugs. J Clin Psychiatry 1983; 44: 301303.Google ScholarPubMed
13.Rendell, M, McGrane, D, Cuesta, M. Fatal compulsive water drinking. JAMA 1978; 240: 25572559.CrossRefGoogle ScholarPubMed
14.Vieweg, WVR, David, JJ, Rowe, WT, Wampler, GJ, Burns, WJ, Spradlin, WW. Death from self-induced water intoxication among patients with schizophrenic disorders. J Nerv Ment Dis 1985; 173: 161165.CrossRefGoogle ScholarPubMed
15.Jose, CJ, Evenson, RC, Mallya, AR. Self-induced water intoxication: a comparison of 34 cases with matched controls. J Clin Psychiatry 1986; 47: 368370.Google Scholar
16.Harrison, G. The abuse of anti-cholinergic drugs in adolescents. Br J Psychiatry 1980; 137: 495.CrossRefGoogle ScholarPubMed
17.Lader, M, Herrington, R. Biological treatments in psychiatry. Oxford: Oxford University Press, 1990: 221.Google Scholar